Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 4/20 | 0.60 |
| ▸ | MRGPRX1 | Q96LB2 | 8/20 | 0.57 |
| ▸ | TSPO | P30536 | 2/20 | 0.52 |
| ▸ | HRH1 | P35367 | 1/20 | 0.48 |
| ▸ | MAP2K4 | P45985 | 2/20 | 0.43 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.41 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23877500 | 0.90 | ACLY (0.53) | ACLYMRGPRX1TSPOHRH1MAP2K4 | |
| SCHEMBL221906 | 0.81 | ACLY (0.49) | ACLYCLCN2KDM4EGRIK1 | |
| SCHEMBL23879514 | 0.81 | KDM4E (0.53) | ACLYKDM4E | |
| SCHEMBL14830605 | 0.80 | MRGPRX1 (0.48) | ACLYMRGPRX1TSPOHRH1MAP2K4 | |
| SCHEMBL23141451 | 0.79 | MRGPRX1 (0.54) | ACLYMRGPRX1TSPOHRH1MAP2K4 | |
| SCHEMBL15847536 | 0.79 | MRGPRX1 (0.59) | MRGPRX1TSPOHRH1MAP2K4 | |
| SCHEMBL31393942 | 0.78 | ACLY (0.62) | ACLYMRGPRX1TSPOKDM4E | |
| SCHEMBL21384590 | 0.77 | ACLY (0.48) | ACLYMRGPRX1 | |
| SCHEMBL21384569 | 0.77 | ACLY (0.48) | ACLYMRGPRX1TSPOHRH1KDM4E | |
| SCHEMBL23141273 | 0.77 | MRGPRX1 (0.52) | ACLYMRGPRX1TSPOHRH1MAP2K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2938338-A2 | NOVEL ANTIVIRAL AGENTS AGAINST HBV INFECTION | Drexel University (US) | 2015-11-04 | — | — | EP | disclosed |
| WO-2014106019-A2 | NOVEL ANTIVIRAL AGENTS AGAINST HBV INFECTION | PHILADELPHIA HEALTH & EDUCATION CORPORATION, D/B/A DREXEL (US) | 2014-07-03 | — | — | WO | disclosed |