Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 2/20 | 0.48 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.42 |
| ▸ | KCNK10 | P57789 | 1/20 | 0.42 |
| ▸ | MRGPRX1 | Q96LB2 | 7/20 | 0.39 |
| ▸ | TSPO | P30536 | 2/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | BRAF | P15056 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21384577 | 0.85 | MRGPRX1 (0.42) | ACLYMRGPRX1TSPOSIRT6HRH1 | |
| SCHEMBL21384590 | 0.83 | ACLY (0.48) | ACLYMRGPRX1 | |
| SCHEMBL15847893 | 0.77 | ACLY (0.60) | ACLYMRGPRX1TSPOHRH1KDM4E | |
| SCHEMBL21384564 | 0.77 | METAP2 (0.56) | ACLYMRGPRX1TSPOTDP1KDM4E | |
| SCHEMBL31433781 | 0.77 | ROCK2 (0.48) | KCNK2KCNK10TDP1KDM4E | |
| SCHEMBL21381491 | 0.72 | ACLY (0.61) | ACLYMRGPRX1KDM4E | |
| SCHEMBL16004173 | 0.72 | KCNK2 (0.49) | KCNK2KCNK10TDP1KDM4E | |
| SCHEMBL15847815 | 0.71 | ACLY (0.51) | ACLYMRGPRX1TSPOBRAFKDM4E | |
| Hydrochloric Acid SCHEMBL21988903 | 0.71 | KCNK2 (0.48) | KCNK2KCNK10SIRT6TDP1KDM4E | |
| Hydrochloric Acid SCHEMBL15994581 | 0.71 | KCNK2 (0.48) | KCNK2KCNK10SIRT6TDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019179436-A1 | ACID AMIDE COMPOUND AND USE THEREOF IN TREATMENT OF CANCERS | 成都海创药业有限公司 | 2019-09-26 | — | — | WO | disclosed |