Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 1/20 | 0.74 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.69 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.68 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.68 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.68 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.68 |
| ▸ | APP | P05067 | 3/20 | 0.56 |
| ▸ | CA1 | P00915 | 2/20 | 0.56 |
| ▸ | CA2 | P00918 | 2/20 | 0.56 |
| ▸ | CA4 | P22748 | 1/20 | 0.56 |
| ▸ | CA6 | P23280 | 1/20 | 0.56 |
| ▸ | BCL2 | P10415 | 1/20 | 0.55 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.55 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.53 |
| ▸ | IGF1R | P08069 | 1/20 | 0.53 |
| ▸ | HNF4A | P41235 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1584791 | 0.85 | IDH1 (1.00) | IDH1CA1CA2CA4CA6 | |
| SCHEMBL928289 | 0.83 | ALOX5 (1.00) | ALOX5APPBCL2L1ACMSDALOX15 | |
| SCHEMBL29848221 | 0.83 | ALOX5 (1.00) | ALOX5APPBCL2L1ACMSDALOX15 | |
| SCHEMBL3628377 | 0.81 | BACE1 (0.57) | IDH1ALOX5CYP17A1CYP3A4CYP19A1 | |
| SCHEMBL18770369 | 0.81 | CYP17A1 (1.00) | ALOX5CYP17A1CYP3A4CYP19A1CYP11B1 | |
| Methane SCHEMBL28271157 | 0.81 | ALOX5 (0.95) | ALOX5APPBCL2L1ACMSDALOX15 | |
| SCHEMBL27714322 | 0.81 | ALOX5 (0.95) | ALOX5APPBCL2L1ACMSDALOX15 | |
| SCHEMBL198432 | 0.80 | CALM1 (0.75) | IDH1CYP17A1CYP3A4CYP19A1CYP11B1 | |
| SCHEMBL28053825 | 0.79 | ALOX5 (0.83) | ALOX5CYP17A1CYP3A4CYP19A1CYP11B1 | |
| SCHEMBL27880220 | 0.79 | ALOX5 (0.83) | ALOX5CYP17A1CYP3A4CYP19A1CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0213454-B1 | HEAT SENSITIVE RECORDING SHEETS CONTAINING SULFONE DERIVATIVES | KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) | 1992-12-02 | — | — | EP | claimed |