Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | KDM4A | O75164 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15855872 | 1.00 | EPHX2 (0.52) | EPHX2POLBKDM4AKMT2ACYP2D6 | |
| SCHEMBL5322284 | 0.83 | POLB (0.59) | POLBKDM4AKMT2ACYP2D6CYP2C9 | |
| SCHEMBL15855811 | 0.77 | MEN1 (0.47) | EPHX2KMT2ACYP2D6CYP2C19LMNA | |
| SCHEMBL15855809 | 0.77 | MEN1 (0.47) | EPHX2KMT2ACYP2D6CYP2C19LMNA | |
| SCHEMBL28616879 | 0.77 | ALDH1A1 (0.42) | EPHX2KMT2ACA1CA2L3MBTL1 | |
| SCHEMBL15855858 | 0.75 | LTA4H (0.55) | KMT2ANPC1RAB9AMEN1ALDH1A1 | |
| SCHEMBL15855859 | 0.75 | LTA4H (0.55) | KMT2ANPC1RAB9AMEN1ALDH1A1 | |
| SCHEMBL15855863 | 0.75 | L3MBTL1 (0.49) | POLBKMT2ACA1CA2L3MBTL1 | |
| SCHEMBL15855861 | 0.75 | L3MBTL1 (0.49) | POLBKMT2ACA1CA2L3MBTL1 | |
| SCHEMBL15855903 | 0.74 | CNR1 (0.56) | EPHX2KMT2AL3MBTL1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8772307-B2 | Substituted spiro compounds and their use for producing pain-relief medicaments | GRUENENTHAL GMBH (DE) | 2014-07-08 | — | — | US | disclosed |