SCHEMBL15856403

SCHEMBL15856403

CN(c1ccccc1F)c1cc(-c2ccc(-c3ccccc3)cc2)cc(-c2ccccc2)c1F

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A9 P48067 2/20 0.35
ACLY P53396 1/20 0.34
PTGS1 P23219 2/20 0.34
HPRT1 P00492 1/20 0.34
TACR1 P25103 1/20 0.34
AKR1C2 P52895 2/20 0.33
AKR1C1 Q04828 2/20 0.33
TAAR1 Q96RJ0 1/20 0.32
PTPN1 P18031 2/20 0.31
PTPRC P08575 1/20 0.31
KDM4E B2RXH2 1/20 0.31
USP2 O75604 1/20 0.31
ALDH1A1 P00352 1/20 0.31
DHODH Q02127 2/20 0.31
MEN1 O00255 1/20 0.31
FABP2 P12104 1/20 0.31
TSHR P16473 1/20 0.31
AKR1C4 P17516 1/20 0.31
ADRA2B P18089 1/20 0.31
CHRM3 P20309 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15856398 1.00 SLC6A9 (0.35) SLC6A9ACLYPTGS1HPRT1TACR1
SCHEMBL15856437 0.98 PTGS1 (0.35) SLC6A9ACLYPTGS1HPRT1TACR1
SCHEMBL15856326 0.94 ACLY (0.36) SLC6A9ACLYPTGS1HPRT1TACR1
SCHEMBL15856329 0.91 ACLY (0.36) SLC6A9ACLYPTGS1TACR1AKR1C2
SCHEMBL15856348 0.91 ESR1 (0.36) SLC6A9ACLYAKR1C2PTGS2AKR1C3
SCHEMBL15856343 0.91 ESR1 (0.36) SLC6A9ACLYAKR1C2PTGS2AKR1C3
SCHEMBL15856457 0.89 CA12 (0.39) SLC6A9ACLYAKR1C2AKR1C3
SCHEMBL15856339 0.89 CA12 (0.39) SLC6A9ACLYAKR1C2AKR1C3
SCHEMBL15856409 0.87 HSD17B1 (0.36) SLC6A9ACLYAKR1C2PTGS2AKR1C3
SCHEMBL15856429 0.86 AKR1C3 (0.36) SLC6A9ACLYAKR1C2AKR1C3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140183468-A1 PYRENE-BASED COMPOUND AND ORGANIC LIGHT-EMITTING DIODE COMPRISING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2014-07-03 US disclosed