Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 5/20 | 0.50 |
| ▸ | CA2 | P00918 | 5/20 | 0.50 |
| ▸ | CA12 | O43570 | 3/20 | 0.48 |
| ▸ | CA9 | Q16790 | 3/20 | 0.48 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.44 |
| ▸ | STK10 | O94804 | 1/20 | 0.43 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | XDH | P47989 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | FNTA | P49354 | 1/20 | 0.40 |
| ▸ | FNTB | P49356 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15856485 | 0.87 | CA1 (0.50) | CA1CA2CA12CA9STK10 | |
| SCHEMBL14926516 | 0.83 | CYP11B2 (0.47) | EGLN2ALDH1A1CYP2A6CYP11B1CYP11B2 | |
| SCHEMBL16945545 | 0.82 | ALDH1A1 (0.40) | CA1CA2CA12CA9EGLN2 | |
| SCHEMBL2154193 | 0.80 | CYP11B2 (0.53) | EGLN2ALDH1A1CYP2A6CYP11B1CYP11B2 | |
| SCHEMBL15853128 | 0.80 | CA1 (0.46) | CA1CA2STK10SLKALDH1A1 | |
| SCHEMBL23191186 | 0.79 | EGLN2 (0.40) | CA1CA2EGLN2STK10SLK | |
| SCHEMBL24276248 | 0.79 | ALDH1A1 (0.50) | CA1CA2CA12CA9EGLN2 | |
| SCHEMBL24276249 | 0.79 | ALDH1A1 (0.50) | CA1CA2CA12CA9EGLN2 | |
| SCHEMBL26750980 | 0.78 | CA1 (0.51) | CA1CA2STK10SLKALDH1A1 | |
| SCHEMBL10051189 | 0.78 | CYP1A2 (0.49) | CA1CA2CA12CA9MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140183468-A1 | PYRENE-BASED COMPOUND AND ORGANIC LIGHT-EMITTING DIODE COMPRISING THE SAME | SAMSUNG DISPLAY CO., LTD. (KR) | 2014-07-03 | — | — | US | disclosed |