SCHEMBL15856485

SCHEMBL15856485

Cc1ccc(C#N)cc1-c1cccc2ccccc12

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.50
CA2 P00918 3/20 0.50
STK10 O94804 1/20 0.43
SLK Q9H2G2 1/20 0.43
FNTA P49354 1/20 0.43
FNTB P49356 1/20 0.43
ALDH1A1 P00352 2/20 0.41
CYP2A6 P11509 2/20 0.41
MCL1 Q07820 1/20 0.40
MAOA P21397 1/20 0.40
MAOB P27338 1/20 0.40
PIM1 P11309 1/20 0.40
ALOX15 P16050 3/20 0.40
KDM4E B2RXH2 2/20 0.40
TSHR P16473 2/20 0.40
MEN1 O00255 1/20 0.40
HCRTR1 O43613 1/20 0.40
GLA P06280 1/20 0.40
POLB P06746 1/20 0.40
GAA P10253 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15856482 0.87 CA1 (0.50) CA1CA2STK10SLKFNTA
SCHEMBL18934546 0.83 AR (0.46) FNTAFNTBALDH1A1CYP2A6KDM4E
SCHEMBL5099580 0.81 CA1 (0.50) CA1CA2STK10SLKFNTA
SCHEMBL15853127 0.80 CA1 (0.46) CA1CA2STK10SLKFNTA
SCHEMBL23191192 0.79 ALDH1A1 (0.40) CA1CA2STK10SLKALDH1A1
SCHEMBL17954835 0.79 TDP2 (0.36) CA1CA2FNTAFNTBALDH1A1
SCHEMBL8105948 0.78 MAOA (0.53) CA1CA2ALDH1A1CYP2A6MAOA
SCHEMBL15853128 0.77 CA1 (0.46) CA1CA2STK10SLKFNTA
SCHEMBL38656851 0.77 CA1 (0.56) CA1CA2STK10SLKCYP2A6
SCHEMBL31428959 0.77 CA1 (0.43) CA1CA2STK10SLKFNTA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140183468-A1 PYRENE-BASED COMPOUND AND ORGANIC LIGHT-EMITTING DIODE COMPRISING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2014-07-03 US disclosed