SCHEMBL15856497

SCHEMBL15856497

Cc1ccc(-c2cccc3ccccc23)c(C#N)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRM2 Q14416 1/20 0.52
XDH P47989 1/20 0.52
MCL1 Q07820 1/20 0.47
MAOA P21397 1/20 0.47
MAOB P27338 1/20 0.47
CA1 P00915 3/20 0.45
CA2 P00918 3/20 0.45
CYP1A2 P05177 1/20 0.41
CYP2A6 P11509 1/20 0.41
PIM1 P11309 2/20 0.40
ALOX15 P16050 3/20 0.40
KDM4E B2RXH2 2/20 0.40
MEN1 O00255 1/20 0.40
HCRTR1 O43613 1/20 0.40
ALDH1A1 P00352 1/20 0.40
GLA P06280 1/20 0.40
POLB P06746 1/20 0.40
GAA P10253 1/20 0.40
HPGD P15428 1/20 0.40
TSHR P16473 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15856480 0.87 MCL1 (0.47) XDHMCL1MAOAMAOBCA1
SCHEMBL23625611 0.85 GRM2 (0.52) GRM2XDHTSHR
SCHEMBL29038987 0.84 CYP1A2 (0.49) GRM2XDHMCL1MAOAMAOB
SCHEMBL7624975 0.83 GRM2 (0.49) GRM2KDM4EALDH1A1GAAHPGD
SCHEMBL28203557 0.81 CA1 (0.60) XDHMCL1CA1CA2PIM1
SCHEMBL3478696 0.80 GRM2 (0.48) GRM2MAOAMAOBCYP1A2CYP2A6
SCHEMBL15853131 0.80 XDH (0.46) XDHMCL1CA1CA2PIM1
SCHEMBL29293789 0.80 TSHR (0.50) GRM2ALOX15MEN1GLAHPGD
SCHEMBL2353695 0.79 CA1 (0.53) XDHMCL1CA1CA2PIM1
SCHEMBL20561064 0.79 MCL1 (0.58) XDHMCL1CA1CA2CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140183468-A1 PYRENE-BASED COMPOUND AND ORGANIC LIGHT-EMITTING DIODE COMPRISING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2014-07-03 US disclosed