Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD2 | Q9HC29 | 6/20 | 0.57 |
| ▸ | NOD1 | Q9Y239 | 6/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | CRHBP | P24387 | 1/20 | 0.55 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.55 |
| ▸ | F10 | P00742 | 2/20 | 0.51 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | GLA | P06280 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28659548 | 0.84 | NOD2 (0.57) | NOD2NOD1MEN1KMT2AKDM4E | |
| SCHEMBL7644354 | 0.82 | NOD2 (0.56) | NOD2NOD1MEN1KMT2AKDM4E | |
| SCHEMBL10380141 | 0.81 | NOD2 (0.51) | NOD2NOD1MEN1KMT2AKDM4E | |
| SCHEMBL1092502 | 0.81 | KDM4E (0.62) | NOD2NOD1MEN1KMT2AKDM4E | |
| SCHEMBL389014 | 0.81 | NOD2 (0.61) | NOD2NOD1MEN1KMT2AKDM4E | |
| SCHEMBL3651263 | 0.81 | NOD2 (0.65) | NOD2NOD1MEN1KMT2AKDM4E | |
| SCHEMBL4740839 | 0.79 | NOD2 (0.60) | NOD2NOD1MEN1KMT2AKDM4E | |
| SCHEMBL6988991 | 0.79 | NOD2 (0.71) | NOD2NOD1MEN1KMT2AKDM4E | |
| SCHEMBL3259707 | 0.79 | NOD2 (0.71) | NOD2NOD1MEN1KMT2AKDM4E | |
| SCHEMBL4791517 | 0.79 | NOD2 (0.60) | NOD2NOD1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011048611-A1 | NOVEL FUSED PYRIDAZINE DERIVATIVES | TORRENT PHARMACEUTICALS LIMITED (IN) | 2011-04-28 | — | — | WO | disclosed |