SCHEMBL15859481

SCHEMBL15859481

N#CC1CC=Cc2cc3ccccc3cc21

nearest known ligand 0.32

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CYP2D6 P10635 1/20 0.30
SLC6A2 P23975 1/20 0.30
SLC6A4 P31645 1/20 0.30
SLC6A3 Q01959 1/20 0.30
KCNH2 Q12809 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7753185 0.83 CYP2D6 (0.30) CYP2D6SLC6A2SLC6A4SLC6A3KCNH2
SCHEMBL9521913 0.79 ATM (0.36) CA1CA2
SCHEMBL1313656 0.74 CYP1A2 (0.33) CA1CA2CYP2D6SLC6A2SLC6A4
SCHEMBL25549138 0.74 ALDH1A1 (0.33) CYP2D6SLC6A2SLC6A4SLC6A3KCNH2
SCHEMBL5025415 0.74 CYP2A6 (0.33) CYP2D6SLC6A2SLC6A4SLC6A3KCNH2
SCHEMBL10878544 0.71 TDP1 (0.31) CYP2D6SLC6A2SLC6A4SLC6A3KCNH2
SCHEMBL11221810 0.71 CA1 (0.33) CA1CA2SLC6A4
SCHEMBL28132004 0.70 CYP2A6 (0.36) CYP2D6SLC6A2SLC6A4SLC6A3KCNH2
SCHEMBL11433359 0.69 POLB (0.38)
SCHEMBL6985110 0.68 MEN1 (0.35) CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2607349-B1 Electrocarboxylation synthesis for obtaining intermediates useful for the synthesis of span derivatives ESPA OLA DE CARBUROS METALICOS S A SOC (ES) 2014-07-09 EP disclosed