Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Nitrophenolate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 4/20 | 0.57 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.51 |
| ▸ | CTSB | P07858 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | CTSD | P07339 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALPL | P05186 | 1/20 | 0.44 |
| ▸ | ALPI | P09923 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nitrophenolate SCHEMBL8469921 | 1.00 | GPR35 (0.57) | GPR35KCNMA1CTSBALDH1A1MAPK1 | |
| Nitrophenolate SCHEMBL27655837 | 0.98 | GPR35 (0.55) | GPR35KCNMA1CTSBALDH1A1MAPK1 | |
| Nitrophenolate SCHEMBL27884327 | 0.92 | GPR35 (0.53) | GPR35KCNMA1CTSBALDH1A1MAPK1 | |
| Nitrophenolate SCHEMBL28029048 | 0.91 | GPR35 (0.65) | GPR35KCNMA1CTSBALDH1A1MAPK1 | |
| Nitrophenolate SCHEMBL29360402 | 0.91 | GPR35 (0.65) | GPR35KCNMA1CTSBALDH1A1MAPK1 | |
| Nitrophenolate SCHEMBL26026 | 0.91 | GPR35 (0.65) | GPR35KCNMA1CTSBALDH1A1MAPK1 | |
| Nitrophenolate SCHEMBL11344901 | 0.89 | GPR35 (0.63) | GPR35KCNMA1CTSBALDH1A1MAPK1 | |
| Nitrophenolate SCHEMBL10996867 | 0.89 | GPR35 (0.63) | GPR35KCNMA1CTSBALDH1A1MAPK1 | |
| Nitrophenolate SCHEMBL10496084 | 0.89 | GPR35 (0.63) | GPR35KCNMA1CTSBALDH1A1MAPK1 | |
| Nitrophenolate SCHEMBL325409 | 0.89 | GPR35 (0.63) | GPR35KCNMA1CTSBALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 287 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115096882-B | Alkaline phosphatase detection kit and preparation method thereof | 北京安图生物工程有限公司 | 2025-05-23 | — | — | CN | claimed |
| CN-115096882-A | Alkaline phosphatase detection kit and preparation method thereof | 北京安图生物工程有限公司 | 2022-09-23 | — | — | CN | claimed |
| EP-2972345-A1 | A FLOW-THROUGH CELL COUNTING ASSAY | Allied Innovative Systems, LLC (US) | 2016-01-20 | — | — | EP | claimed |
| WO-2014149310-A1 | A FLOW-THROUGH CELL COUNTING ASSAY | ALLIED INNOVATIVE SYSTEMS, LLC (US) | 2014-09-25 | — | — | WO | claimed |
| CN-103271080-B | Phosphate salt plant growth conditioning agent and application thereof | UNIV QINGDAO SCIENCE & TECHNOLOGY | 2014-09-17 | — | — | CN | claimed |
| CN-103271080-A | Phosphate salt plant growth conditioning agent and application thereof | UNIV QINGDAO SCIENCE & TECHNOLOGY | 2013-09-04 | — | — | CN | claimed |
| CN-102099375-A | Anti-idiotypic monoclonal antibody against envelope protein vp28 of shrimp white spot syndrome virus and the preparation method thereof | OCEAN UNIV CHINA | 2011-06-15 | — | — | CN | claimed |
| EP-0642587-A4 | SYSTEM FOR MEASURING PROTEOLYTIC ACTIVITY OF PERIODONTOPATHOGENIC BACTERIA. | UNIV MICHIGAN (US) | 1997-03-19 | — | — | EP | claimed |
| EP-0642587-A1 | SYSTEM FOR MEASURING PROTEOLYTIC ACTIVITY OF PERIODONTOPATHOGENIC BACTERIA | THE UNIVERSITY OF MICHIGAN (US) | 1995-03-15 | — | — | EP | claimed |
| WO-1993024651-A1 | SYSTEM FOR MEASURING PROTEOLYTIC ACTIVITY OF PERIODONTOPATHOGENIC BACTERIA | UNIVERSITY OF MICHIGAN (US) | 1993-12-09 | — | — | WO | claimed |
| US-5116735-A | Colorimetric assay, hydrolysis of chromogen | THE UNIVERSITY OF MICHIGAN (US) | 1992-05-26 | — | — | US | claimed |
| EP-0369362-A2 | Substrate composition for alkaline phosphatase and method for assay using same | Becton, Dickinson and Company (US) | 1990-05-23 | — | — | EP | claimed |
| CN-115096882-B | Alkaline phosphatase detection kit and preparation method thereof | 北京安图生物工程有限公司 | 2025-05-23 | — | — | CN | disclosed |
| CN-115096882-B | Alkaline phosphatase detection kit and preparation method thereof | 北京安图生物工程有限公司 | 2025-05-23 | — | — | CN | disclosed |
| US-20240011108-A1 | MASS SPECTROMETRY-BASED METHODS AND KITS FOR NUCLEIC ACID DETECTION AND DISEASE DIAGNOSTIC | YYZ PHARMATECH INC. (CA) | 2024-01-11 | — | — | US | disclosed |
| EP-4232598-A1 | MASS SPECTROMETRY-BASED METHODS AND KITS FOR NUCLEIC ACID DETECTION AND DISEASE DIAGNOSTIC | YYZ Pharmatech Inc. (CA) | 2023-08-30 | — | — | EP | disclosed |
| EP-0319686-A2 | Method for assaying a target substance in a minute amount of nipple discharge and device for such an assay | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1989-06-14 | — | — | EP | disclosed |
| EP-0274343-A1 | A system of reactants involving an apo-enzyme useful in immunological analysis and a method for carrying out immunoassays with this system | IntraCel Corporation (BB) | 1988-07-13 | — | — | EP | disclosed |
| CN-85109047-A | Applying biological luminous introduce that other exogenous genetic marker detects or the characterization test sample in microorganism | — | 1987-06-03 | — | — | CN | disclosed |
| US-4132598-A | Stabilized liquid phosphate containing diagnostic compositions and method of preparing same | MEDICAL ANALYSIS SYSTEMS, INC. | 1979-01-02 | — | — | US | disclosed |