SCHEMBL15859643

SCHEMBL15859643

CN(CCO)c1cccc2c1C(=O)c1ccccc1C2=O

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 7/20 0.72
KMT2A Q03164 7/20 0.72
PABPC1 P11940 3/20 0.72
MAPT P10636 8/20 0.63
ALDH1A1 P00352 8/20 0.63
L3MBTL1 Q9Y468 6/20 0.63
MAPK1 P28482 5/20 0.63
TDP1 Q9NUW8 3/20 0.63
EGFR P00533 3/20 0.63
LMNA P02545 2/20 0.63
NSD2 O96028 1/20 0.63
KDM4E B2RXH2 2/20 0.51
SMN1; SMN2 Q16637 4/20 0.50
NPSR1 Q6W5P4 3/20 0.50
RAD52 P43351 3/20 0.50
POLB P06746 2/20 0.50
HTT P42858 2/20 0.50
BLM P54132 2/20 0.50
RECQL P46063 1/20 0.50
RAB9A P51151 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15859646 0.95 MEN1 (0.64) MEN1KMT2APABPC1MAPTALDH1A1
SCHEMBL7063623 0.94 MEN1 (0.62) MEN1KMT2APABPC1MAPTALDH1A1
SCHEMBL31218594 0.86 KMT2A (0.58) MEN1KMT2APABPC1MAPTALDH1A1
SCHEMBL30231841 0.84 ALDH1A1 (0.54) MEN1KMT2APABPC1MAPTALDH1A1
SCHEMBL12858677 0.84 MEN1 (1.00) MEN1KMT2APABPC1MAPTALDH1A1
SCHEMBL7156890 0.81 KMT2A (0.67) MEN1KMT2APABPC1MAPTALDH1A1
SCHEMBL3420793 0.80 ALDH1A1 (0.56) MEN1KMT2APABPC1MAPTALDH1A1
SCHEMBL187706 0.78 L3MBTL1 (1.00) MEN1KMT2APABPC1MAPTALDH1A1
SCHEMBL9844713 0.78 ALDH1A1 (0.79) MEN1KMT2APABPC1MAPTALDH1A1
SCHEMBL11286361 0.78 MEN1 (0.86) MEN1KMT2APABPC1MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11378546-B2 PH Meter PARKER HANNIFIN CORP (US) 2022-07-05 US disclosed
EP-3734264-A1 PH METER Parker Hannifin Corporation (US) 2020-11-04 EP disclosed
US-20200064307-A1 pH METER PARKER HANNIFIN CORP (US) 2020-02-27 US disclosed
US-20150346144-A1 PH METER PARKER-HANNIFIN CORPORATION 2015-12-03 US disclosed
US-20150346144-A1 PH METER PARKER-HANNIFIN CORPORATION 2015-12-03 US disclosed
WO-2014106066-A1 PH METER SENOVA SYSTEMS, INC. (US) 2014-07-03 WO disclosed