Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.79 |
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.79 |
| ▸ | MAPK1 | P28482 | 7/20 | 0.79 |
| ▸ | MAPT | P10636 | 6/20 | 0.79 |
| ▸ | EGFR | P00533 | 4/20 | 0.79 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.79 |
| ▸ | LMNA | P02545 | 2/20 | 0.79 |
| ▸ | NSD2 | O96028 | 1/20 | 0.79 |
| ▸ | PABPC1 | P11940 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.56 |
| ▸ | RAB9A | P51151 | 5/20 | 0.54 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.52 |
| ▸ | MAOA | P21397 | 3/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.50 |
| ▸ | CDC25B | P30305 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7601575 | 0.88 | ALDH1A1 (0.63) | ALDH1A1L3MBTL1MAPK1MAPTEGFR | |
| SCHEMBL187706 | 0.88 | L3MBTL1 (1.00) | ALDH1A1L3MBTL1MAPK1MAPTEGFR | |
| SCHEMBL28208845 | 0.85 | ALDH1A1 (0.73) | ALDH1A1L3MBTL1MAPK1MAPTEGFR | |
| SCHEMBL9359548 | 0.83 | ALDH1A1 (0.71) | ALDH1A1L3MBTL1MAPK1MAPTEGFR | |
| SCHEMBL7170509 | 0.82 | L3MBTL1 (0.70) | ALDH1A1L3MBTL1MAPK1MAPTEGFR | |
| SCHEMBL18984785 | 0.81 | MAPT (0.88) | ALDH1A1L3MBTL1MAPK1MAPTEGFR | |
| SCHEMBL11225143 | 0.80 | ALDH1A1 (0.67) | ALDH1A1L3MBTL1MAPK1MAPTEGFR | |
| SCHEMBL5535931 | 0.80 | ALDH1A1 (0.85) | ALDH1A1L3MBTL1MAPK1MAPTEGFR | |
| SCHEMBL2362908 | 0.80 | MAPT (0.85) | ALDH1A1L3MBTL1MAPK1MAPTEGFR | |
| SCHEMBL9192003 | 0.80 | L3MBTL1 (0.67) | ALDH1A1L3MBTL1MAPK1MAPTEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0457721-A1 | NIR-absorbant dyes | CIBA-GEIGY AG (CH) | 1991-11-21 | — | — | EP | disclosed |