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SCHEMBL15861007

SCHEMBL15861007

CC1(C)c2ccccc2-c2c1c1c3c4ccccc4n(-c4ccc(N(c5ccc(-c6ccccc6)cc5)c5ccc(-c6ccccc6)cc5)cc4)c3ccc1n2-c1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 2/20 0.35
▸ KDM4E B2RXH2 1/20 0.35
▸ ATM Q13315 1/20 0.35
▸ IL1R1 P14778 1/20 0.34
▸ MEN1 O00255 1/20 0.33
▸ ALDH1A1 P00352 1/20 0.33
▸ MAPT P10636 1/20 0.33
▸ HTT P42858 1/20 0.33
▸ KMT2A Q03164 1/20 0.33
▸ HDAC4 P56524 1/20 0.32
▸ PGR P06401 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15860651 0.93 KDM4E (0.30) L3MBTL1KDM4EATMIL1R1
SCHEMBL15860720 0.89 L3MBTL1 (0.33) L3MBTL1KDM4EATMIL1R1MEN1
SCHEMBL15860782 0.88 TSPO (0.34) L3MBTL1KDM4EATM
SCHEMBL15860815 0.88 — —
SCHEMBL31671 0.88 KDM4E (0.32) L3MBTL1KDM4EATMHDAC4
SCHEMBL31855 0.88 KDM4E (0.32) L3MBTL1KDM4EATMHDAC4
SCHEMBL31831 0.88 KDM4E (0.32) L3MBTL1KDM4EATMHDAC4
SCHEMBL17677022 0.86 PGR (0.33) PGR
SCHEMBL15860730 0.86 L3MBTL1 (0.36) L3MBTL1KDM4EATMIL1R1MEN1
SCHEMBL17777738 0.85 KDM4E (0.35) L3MBTL1KDM4EATMHDAC4PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2014104665-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT INCLUDING SAME 주식회사 두산 (KR) 2014-07-03 — — WO disclosed
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