Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNA2 | P20248 | 3/20 | 0.51 |
| ▸ | CDK2 | P24941 | 3/20 | 0.51 |
| ▸ | CCND3 | P30281 | 3/20 | 0.51 |
| ▸ | CCNK | O75909 | 1/20 | 0.51 |
| ▸ | CDK9 | P50750 | 1/20 | 0.51 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.51 |
| ▸ | CTSC | P53634 | 2/20 | 0.45 |
| ▸ | KDR | P35968 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | CDK4 | P11802 | 3/20 | 0.41 |
| ▸ | CCND1 | P24385 | 3/20 | 0.41 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.41 |
| ▸ | CCND2 | P30279 | 2/20 | 0.41 |
| ▸ | FLT3 | P36888 | 1/20 | 0.40 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.40 |
| ▸ | MERTK | Q12866 | 1/20 | 0.40 |
| ▸ | GAS6 | Q14393 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4065994 | 0.81 | CCNA2 (0.45) | CCNA2CDK2CCND3CCNKCDK9 | |
| SCHEMBL30656321 | 0.75 | CCNA2 (0.46) | CCNA2CDK2CCND3CCNKCDK9 | |
| SCHEMBL15864563 | 0.73 | MEN1 (0.50) | CCNA2CDK2CCND3CCNKCDK9 | |
| SCHEMBL10639645 | 0.73 | NFKB1 (0.55) | CCNA2CDK2CCND3CCNKCDK9 | |
| SCHEMBL1133352 | 0.72 | KMT2A (0.48) | CCNA2CDK2CCND3CCNKCDK9 | |
| SCHEMBL1883319 | 0.72 | KMT2A (0.57) | CCNA2CDK2CCND3CCNKCDK9 | |
| SCHEMBL29544002 | 0.71 | MEN1 (0.67) | KDRMEN1KMT2AMAPK10GFER | |
| SCHEMBL3951276 | 0.71 | MEN1 (0.67) | KDRMEN1KMT2AMAPK10GFER | |
| SCHEMBL6323476 | 0.71 | MEN1 (0.47) | CCNA2CDK2CCND3CCNKCDK9 | |
| SCHEMBL6402766 | 0.71 | KMT2A (0.47) | CCNA2CDK2CCND3CCNKCDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014106800-A2 | SUBSTITUTED 2-AMINO PYRIMIDINE DERIVATIVES AS KINASE INHIBITORS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2014-07-10 | — | — | WO | disclosed |