Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.45 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 5/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | LOXL2 | Q9Y4K0 | 5/20 | 0.33 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 2/20 | 0.32 |
| ▸ | JAK1 | P23458 | 2/20 | 0.32 |
| ▸ | TYK2 | P29597 | 2/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28145192 | 0.98 | HCAR2 (0.44) | HCAR2NLRP3KDM4ECHRM5CYP3A4 | |
| SCHEMBL19013740 | 0.80 | HCAR2 (0.42) | HCAR2NLRP3CHRM5CYP3A4CYP2D6 | |
| SCHEMBL12574385 | 0.79 | MAPT (0.39) | HCAR2NLRP3KDM4ECHRM5CYP3A4 | |
| SCHEMBL15970548 | 0.78 | HCAR2 (0.41) | HCAR2NLRP3CHRM5CYP3A4CYP2D6 | |
| SCHEMBL5515612 | 0.78 | CA2 (0.44) | HCAR2NLRP3CHRM5CYP3A4CYP2D6 | |
| SCHEMBL19013711 | 0.77 | LOXL2 (0.46) | HCAR2NLRP3CHRM5CYP3A4CYP2D6 | |
| SCHEMBL3453513 | 0.76 | CA1 (0.40) | HCAR2KDM4ECA12CA1CA2 | |
| SCHEMBL1348269 | 0.76 | KDM4E (0.32) | KDM4ELOXL2ADORA3SLC6A3 | |
| SCHEMBL23569847 | 0.75 | HCAR2 (0.38) | HCAR2NLRP3CHRM5CYP3A4CYP2D6 | |
| SCHEMBL3474793 | 0.74 | ADORA3 (0.55) | KDM4ELOXL2ADORA3SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2569375-B1 | MODIFIED PIGMENTS | CABOT CORP (US) | 2017-11-22 | — | — | EP | disclosed |
| US-8771411-B2 | Modified pigments | CABOT CORPORATION (US) | 2014-07-08 | — | — | US | disclosed |