Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUSP22 | Q9NRW4 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2757957 | 0.88 | HPGD (0.50) | DUSP22SMN1; SMN2MAPTKMT2AMEN1 | |
| SCHEMBL16095734 | 0.81 | LMNA (0.45) | DUSP22SMN1; SMN2KMT2AMEN1POLB | |
| SCHEMBL2757960 | 0.81 | MAPK8 (0.43) | DUSP22SMN1; SMN2MAPTKMT2AMEN1 | |
| SCHEMBL14679331 | 0.81 | BCHE (0.47) | MAPTKMT2AMEN1POLBMMP1 | |
| SCHEMBL2757938 | 0.77 | MEN1 (0.48) | DUSP22KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL11922670 | 0.77 | ALDH1A1 (0.52) | ALDH1A1HPGDLMNA | |
| SCHEMBL13701692 | 0.76 | KMT2A (0.59) | SMN1; SMN2MAPTKMT2AMEN1POLB | |
| SCHEMBL21097019 | 0.76 | DUSP22 (0.40) | DUSP22KMT2AMEN1POLBLMNA | |
| SCHEMBL21097023 | 0.76 | DUSP22 (0.40) | DUSP22KMT2AMEN1POLBLMNA | |
| SCHEMBL28447168 | 0.76 | ALDH1A1 (0.46) | SMN1; SMN2MAPTKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8772450-B2 | Beta-amino acids | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2014-07-08 | — | — | US | disclosed |