SCHEMBL15865951

SCHEMBL15865951

CNC(=O)Nc1ncnc2c1ncn2C1OC(CO)C(O)C1O

nearest known ligand 0.70

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
BMPR1B O00238 1/20 0.68
ADORA2A P29274 1/20 0.65
ADORA2B P29275 1/20 0.65
SLC29A1 Q99808 2/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3022531 1.00 BMPR1B (0.68) BMPR1BADORA2AADORA2BSLC29A1
SCHEMBL15158098 0.90 SLC29A1 (0.65) ADORA2AADORA2BSLC29A1
SCHEMBL155836 0.89 SLC29A1 (0.75) ADORA2AADORA2BSLC29A1
SCHEMBL155837 0.89 SLC29A1 (0.75) ADORA2AADORA2BSLC29A1
SCHEMBL31307310 0.88 SLC29A1 (0.67) ADORA2AADORA2BSLC29A1
SCHEMBL24920112 0.87 ADORA2A (0.67) ADORA2AADORA2BSLC29A1
SCHEMBL30208521 0.87 ADORA2A (0.67) ADORA2AADORA2BSLC29A1
SCHEMBL28477260 0.87 ADORA2A (0.67) ADORA2AADORA2BSLC29A1
SCHEMBL40635 0.87 ADORA3 (0.72) SLC29A1
SCHEMBL20801120 0.87 ADORA3 (0.72) SLC29A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2164537-B1 ANTI-NO-REFLOW GUIDE WIRE FOR VASCULAR INTERVENTIONAL PROCEDURES ADENOPAINT LLC (US) 2017-03-08 EP disclosed
US-8771310-B2 Anti-no-reflow guide wire for vascular interventional procedures ADENOPAINT, LLC (US) 2014-07-08 US disclosed