SCHEMBL158679

SCHEMBL158679

O=C(O)c1cc(OC(F)(F)C(F)OC(F)(F)C(F)(OC(F)(F)C(F)(F)C(F)(F)F)C(F)(F)F)cc(C(=O)O)c1

nearest known ligand 0.37

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.37
TSHR P16473 1/20 0.37
HSD17B10 Q99714 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1440099 0.90 ALDH1A1 (0.42) ALDH1A1TSHRHSD17B10
SCHEMBL158541 0.89
SCHEMBL15675519 0.88 ALDH1A1 (0.52) ALDH1A1TSHRHSD17B10
SCHEMBL254711 0.87 NOTUM (0.33)
SCHEMBL15715137 0.87 ALDH1A1 (0.36) ALDH1A1TSHRHSD17B10
SCHEMBL15696575 0.87 ALDH1A1 (0.36) ALDH1A1TSHRHSD17B10
SCHEMBL159682 0.81 ALDH1A1 (0.34) ALDH1A1TSHRHSD17B10
SCHEMBL15676233 0.80 ALDH1A1 (0.39) ALDH1A1TSHRHSD17B10
SCHEMBL15675525 0.80 ALDH1A1 (0.39) ALDH1A1TSHRHSD17B10
SCHEMBL2436674 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2658923-B1 FLUORINATED POLYESTER BLEND DU PONT (US) 2017-02-01 EP claimed
EP-2659037-B1 CARPETS PREPARED FROM YARNS COMPRISING A FLUORINATED POLYESTER BLEND DU PONT (US) 2017-07-26 EP disclosed
EP-2659040-B1 A FABRIC PREPARED FROM FLUORINATED POLYESTER BLEND YARNS DU PONT (US) 2017-03-01 EP disclosed
EP-2658923-B1 FLUORINATED POLYESTER BLEND DU PONT (US) 2017-02-01 EP disclosed
EP-2659036-B1 FIBERS AND YARNS FROM A FLUORINATED POLYESTER BLEND DU PONT (US) 2015-07-29 EP disclosed
US-9017788-B2 Carpets prepared from yarns comprising a fluorinated polyester blend E I DU PONT DE NEMOURS AND COMPANY (US) 2015-04-28 US disclosed
US-8889256-B2 Fabric prepared from fluorinated polyester blend yarns E I DU PONT DE NEMOURS AND COMPANY (US) 2014-11-18 US disclosed
US-8772420-B2 Fluorinated polyester blend E I DU PONT DE NEMOURS AND COMPANY (US) 2014-07-08 US disclosed
US-20140134420-A1 CROSSLINKED COPOLYMERS COMPRISING FLUOROVINYLETHER FUNCTIONALIZED AROMATIC MOIETIES E I DU PONT DE NEMOURS AND COMPANY (US) 2014-05-15 US disclosed
US-20140135456-A1 ARTICLES MADE FROM CROSSLINKED COPOLYMERS COMPRISING FLUOROVINYLETHER FUNCTIONALIZED AROMATIC MOIETIES E I DU PONT DE NEMOURS AND COMPANY (US) 2014-05-15 US disclosed
EP-2473547-A2 POLYARAMID COMPRISING FLUOROVINYLETHER FUNCTIONALIZED AROMATIC MOIETIES E. I. du Pont de Nemours and Company (US) 2012-07-11 EP disclosed
EP-2473556-A2 POLYESTER FILMS WITH IMPROVED OIL REPELLENCY E. I. du Pont de Nemours and Company (US) 2012-07-11 EP disclosed
EP-2473543-A2 POLYESTERS COMPRISING FLUOROVINYLETHER FUNCTIONALIZED AROMATIC MOIETIES E. I. du Pont de Nemours and Company (US) 2012-07-11 EP disclosed
WO-2012030352-A1 POLYARAMID FILMS COMPRISING FLUOROVINYLETHER FUNCTIONALIZED AROMATIC MOIETIES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2012-03-08 WO disclosed
US-20110218317-A1 POLYESTERS COMPRISING FLUOROVINYLETHER FUNCTIONALIZED AROMATIC MOIETIES E.I. DU PONT DE NEMOURS AND COMPANY (US) 2011-09-08 US disclosed
US-20110218319-A1 POLYARAMID FILMS COMPRISING FLUOROVINYLETHER FUNCTIONALIZED AROMATIC MOIETIES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-09-08 US disclosed
US-20110218353-A1 FLUOROVINYL ETHER FUNCTIONALIZED AROMATIC DIESTERS, DERIVATIVES THEREOF, AND PROCESS FOR THE PREPARATION THEREOF E.I. DU PONT DE NEMOURS AND COMPANY (US) 2011-09-08 US disclosed
US-20110213118-A1 POLYARAMID COMPRISING FLUOROVINYLETHER FUNCTIONALIZED AROMATIC MOIETIES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-09-01 US disclosed
WO-2011028767-A2 FLUOROETHER FUNCTIONALIZED AROMATIC DIESTERS AND DERIVATIVES THEREOF E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-03-10 WO disclosed
WO-2011028791-A2 POLYARAMID COMPRISING FLUOROVINYLETHER FUNCTIONALIZED AROMATIC MOIETIES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-03-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110218353-A1 FLUOROVINYL ETHER FUNCTIONALIZED AROMATIC DIESTERS, DERIVATIVES THEREOF, AND PROCESS FOR THE PREPARATION THEREOF PFAS, PAH, AFF4 ALDH1A1 3438/4885TSHR 4374/4885HSD17B10 3369/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.