SCHEMBL1586840

SCHEMBL1586840

CC(C)=CCCC(C)=CCCC(C)=CCCC(C)=CCBr

nearest known ligand 0.73

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.73
MAPT P10636 2/20 0.64
MEN1 O00255 2/20 0.64
CYP3A4 P08684 2/20 0.64
ALOX15 P16050 2/20 0.64
ALDH1A1 P00352 1/20 0.64
UGT1A1 P22309 1/20 0.64
SQLE Q14534 7/20 0.61
KDM4E B2RXH2 1/20 0.57
FNTA P49354 1/20 0.52
FNTB P49356 1/20 0.52
ICMT O60725 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9238573 1.00 KMT2A (0.73) KMT2AMAPTMEN1CYP3A4ALOX15
SCHEMBL158266 1.00 KMT2A (0.73) KMT2AMAPTMEN1CYP3A4ALOX15
SCHEMBL255003 1.00 KMT2A (0.73) KMT2AMAPTMEN1CYP3A4ALOX15
SCHEMBL16485660 1.00 KMT2A (0.73) KMT2AMAPTMEN1CYP3A4ALOX15
SCHEMBL2250076 1.00 KMT2A (0.73) KMT2AMAPTMEN1CYP3A4ALOX15
SCHEMBL158315 1.00 KMT2A (0.73) KMT2AMAPTMEN1CYP3A4ALOX15
SCHEMBL11844736 1.00 KMT2A (0.73) KMT2AMAPTMEN1CYP3A4ALOX15
SCHEMBL11844741 1.00 KMT2A (0.73) KMT2AMAPTMEN1CYP3A4ALOX15
SCHEMBL442001 1.00 KMT2A (0.73) KMT2AMAPTMEN1CYP3A4ALOX15
SCHEMBL12293765 1.00 KMT2A (0.73) KMT2AMAPTMEN1CYP3A4ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108627647-B Detection and quantification method of post-translational modification proteomics 四川大学 2020-06-19 CN claimed
US-20040249219-A1 Method of making teprenone BIO-TECHNICAL RESOURCES, A DIVISION OF ARKION LIFE SCIENCES LLC 2004-12-09 US claimed
WO-2002003981-A1 METHOD OF MAKING TEPRENONE DCV, INC. D/B/A BIO-TECHNICAL RESOURCES (US) 2002-01-17 WO claimed
JP-2000500758-A 2000-01-25 JP claimed
EP-0862575-A1 NOVEL GERANYLGERANYL-DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND RELATED PHARMACEUTICAL COMPOSITIONS LABORATORI BALDACCI Spa (IT) 1998-09-09 EP claimed
WO-1997019091-A1 NOVEL GERANYLGERANYL-DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND RELATED PHARMACEUTICAL COMPOSITIONS LABORATORI BALDACCI S.P.A. (IT) 1997-05-29 WO claimed
US-4229356-A Production of vitamin K1 and vitamin K2 WAKUNAGA YAKUHIN KABUSHIKI KAISHA (JP) 1980-10-21 US claimed
JP-1226809-A None JP disclosed
JP-1226843-A None JP disclosed
CN-108627647-B Detection and quantification method of post-translational modification proteomics 四川大学 2020-06-19 CN disclosed
US-20200033361-A1 Detection and Quantitation Method for Proteomics of Post-Translational Modifications SICHUAN UNIVERSITY (CN) 2020-01-30 US disclosed
US-9403791-B1 Coumarin derivatives for cancer therapy WELLESLEY COLLEGE (US) 2016-08-02 US disclosed
US-9388155-B1 Coumarin derivatives for cancer therapy WELLESLEY COLLEGE (US) 2016-07-12 US disclosed
US-4562005-A ANTITUMOR TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1985-12-31 US disclosed
US-4455316-A Polyprenyl esters of acemethacins and anti-inflammatory method of use thereof EISAI CO., LTD. (JP) 1984-06-19 US disclosed
US-4270003-A Hydroquinone derivatives and preparation thereof KURARAY CO., LTD. (JP) 1981-05-26 US disclosed
US-4229356-A Production of vitamin K1 and vitamin K2 WAKUNAGA YAKUHIN KABUSHIKI KAISHA (JP) 1980-10-21 US disclosed
US-4229356-A Production of vitamin K1 and vitamin K2 WAKUNAGA YAKUHIN KABUSHIKI KAISHA (JP) 1980-10-21 US disclosed
US-4169157-A Therapeutic preparations for peptic ulcers comprising aliphatic ketone derivative EISAI CO., LTD. (JP) 1979-09-25 US disclosed
US-4116955-A META-CYCLOPHANE AND A TRANS-TERPENOID, SEPARATION OF ISOMERS TEIJIN LIMITED (JP) 1978-09-26 US disclosed