SCHEMBL2250076

SCHEMBL2250076

CC(C)=CCCC(C)=CCCC(C)=CCCC(C)=CCCC(C)=CCBr

nearest known ligand 0.73

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.73
MAPT P10636 2/20 0.64
MEN1 O00255 2/20 0.64
CYP3A4 P08684 2/20 0.64
ALOX15 P16050 2/20 0.64
ALDH1A1 P00352 1/20 0.64
UGT1A1 P22309 1/20 0.64
SQLE Q14534 7/20 0.61
KDM4E B2RXH2 1/20 0.57
FNTA P49354 1/20 0.52
FNTB P49356 1/20 0.52
ICMT O60725 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9238573 1.00 KMT2A (0.73) KMT2AMAPTMEN1CYP3A4ALOX15
SCHEMBL158266 1.00 KMT2A (0.73) KMT2AMAPTMEN1CYP3A4ALOX15
SCHEMBL255003 1.00 KMT2A (0.73) KMT2AMAPTMEN1CYP3A4ALOX15
SCHEMBL16485660 1.00 KMT2A (0.73) KMT2AMAPTMEN1CYP3A4ALOX15
SCHEMBL1586840 1.00 KMT2A (0.73) KMT2AMAPTMEN1CYP3A4ALOX15
SCHEMBL158315 1.00 KMT2A (0.73) KMT2AMAPTMEN1CYP3A4ALOX15
SCHEMBL11844736 1.00 KMT2A (0.73) KMT2AMAPTMEN1CYP3A4ALOX15
SCHEMBL11844741 1.00 KMT2A (0.73) KMT2AMAPTMEN1CYP3A4ALOX15
SCHEMBL442001 1.00 KMT2A (0.73) KMT2AMAPTMEN1CYP3A4ALOX15
SCHEMBL12293765 1.00 KMT2A (0.73) KMT2AMAPTMEN1CYP3A4ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3018116-B1 VITAMIN K2 INTERMEDIATES KAPPA BIOSCIENCE AS (NO) 2020-10-28 EP disclosed
US-10472314-B2 Process for the preparation of vitamin K2 KAPPA BIOSCIENCE AS (NO) 2019-11-12 US disclosed
US-20170283354-A1 PROCESS FOR THE PREPARATION OF VITAMIN K2 KAPPA BIOSCIENCE AS (NO) 2017-10-05 US disclosed
EP-3018116-A1 VITAMIN K2 INTERMEDIATES Kappa Bioscience As (NO) 2016-05-11 EP disclosed
EP-2346806-B1 PROCESS FOR THE PREPARATION OF VITAMIN K2 KAPPA BIOSCIENCE AS (NO) 2016-01-06 EP disclosed
US-20150210620-A1 PROCESS FOR THE PREPARATION OF VITAMIN K2 KAPPA BIOSCIENCE AS (NO) 2015-07-30 US disclosed
US-9012693-B2 Process for the preparation of vitamin K2 KAPPA BIOSCIENCE AS (NO) 2015-04-21 US disclosed
US-20110207967-A1 PROCESS FOR THE PREPARATION OF VITAMIN K2 KAPPA BIOSCIENCE AS (NO) 2011-08-25 US disclosed
EP-2346806-A1 PROCESS FOR THE PREPARATION OF VITAMIN K2 Kappa Bioscience As (NO) 2011-07-27 EP disclosed
WO-2010034999-A1 CRYSTALLINE MENOQUINONE-7 (VITAMIN K2) KAPPA BIOSCIENCE AS (NO) 2010-04-01 WO disclosed
WO-2010035000-A1 PROCESS FOR THE PREPARATION OF VITAMIN K2 KAPPA BIOSCIENCE AS (NO) 2010-04-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10472314-B2 Process for the preparation of vitamin K2 PROC, VKORC1, VKORC1L1 KMT2A 213/4885MAPT 4698/4885MEN1 28/4885
US-20170283354-A1 PROCESS FOR THE PREPARATION OF VITAMIN K2 PROC, VKORC1, VKORC1L1 KMT2A 206/4885MAPT 4724/4885MEN1 44/4885
US-20110207967-A1 PROCESS FOR THE PREPARATION OF VITAMIN K2 PROC, VKORC1, VKORC1L1 KMT2A 225/4885MAPT 4700/4885MEN1 44/4885
US-20150210620-A1 PROCESS FOR THE PREPARATION OF VITAMIN K2 PROC, VKORC1, VKORC1L1 KMT2A 206/4885MAPT 4724/4885MEN1 44/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.