Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29798791 | 1.00 | LMNA (0.40) | LMNAADRB2CYP2D6BCHEACHE | |
| Hydrochloric Acid SCHEMBL8886084 | 0.99 | LMNA (0.39) | LMNAADRB2CYP2D6BCHEACHE | |
| SCHEMBL11026792 | 0.90 | ADRB2 (0.39) | LMNAADRB2CYP2D6BCHEACHE | |
| Hydrochloric Acid SCHEMBL11055432 | 0.89 | LMNA (0.38) | LMNAADRB2CYP2D6BCHEACHE | |
| SCHEMBL11023914 | 0.84 | LMNA (0.42) | LMNAADRB2CYP2D6BCHEACHE | |
| SCHEMBL11026312 | 0.84 | LMNA (0.50) | LMNAADRB2CYP2D6BCHEACHE | |
| Hydrochloric Acid SCHEMBL11059071 | 0.83 | LMNA (0.41) | LMNAADRB2CYP2D6BCHEACHE | |
| Hydrochloric Acid SCHEMBL10896355 | 0.83 | LMNA (0.51) | LMNAADRB2CYP2D6BCHEACHE | |
| SCHEMBL121592 | 0.83 | ADRB2 (0.38) | LMNAADRB2KMT2AADRB1 | |
| SCHEMBL2720869 | 0.81 | ADRB2 (0.48) | ADRB2KMT2AKDM4ESMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1167 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2522340-A1 | Method of using a thiazole derivative | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2012-11-14 | — | — | EP | claimed |
| US-20120010179-A1 | Methods of using a thiazole derivative | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2012-01-12 | — | — | US | claimed |
| EP-1617819-B1 | RADIOACTIVELY MARKED MICROPARTICLES, METHOD FOR THE PRODUCTION THEREOF AND USE OF THE SAME | BOEHRINGER INGELHEIM INT (DE) | 2011-08-17 | — | — | EP | claimed |
| US-20110014134-A1 | SUSPENSION AEROSOL FORMULATIONS OF PHARMACEUTICAL PRODUCTS | BOEHRINGER INGELHEIM KG (DE) | 2011-01-20 | — | — | US | claimed |
| EP-2269648-A2 | Pharmaceutical compositions based on anticholinergically effective compounds and beta-mimetics | Boehringer Ingelheim Pharma GmbH & Co. KG (DE) | 2011-01-05 | — | — | EP | claimed |
| EP-2269647-A2 | Pharmaceutical compositions based on anticholinergically effective compounds and beta-mimetics | Boehringer Ingelheim Pharma GmbH & Co. KG (DE) | 2011-01-05 | — | — | EP | claimed |
| US-20100272638-A1 | RADIOLABELLED MICROPARTICLES, PROCESSES FOR THE PREPARATION THEREOF AND THE USE THEREOF | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-10-28 | — | — | US | claimed |
| EP-1408967-B1 | PHARMACEUTICAL COMPOSITIONS BASED ON Tiotropium, Ciclesonide AND a BETAMIMETIC AGENT FOR THE TREATMENT OF INFLAMMATORY AND/OR OBSTRUCTIVE RESPIRATORY TRACT DISEASES | BOEHRINGER INGELHEIM PHARMA (DE) | 2009-10-28 | — | — | EP | claimed |
| US-20090104127-A1 | SUSPENSION AEROSOL FORMULATIONS OF PHARMACEUTICAL PRODUCTS | BOEHRINGER INGELHEIM KG (DE) | 2009-04-23 | — | — | US | claimed |
| EP-2040686-A1 | METHODS OF USING A THIAZOLE DERIVATIVE | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2009-04-01 | — | — | EP | claimed |
| WO-1997005136-A1 | IPRATROPIUM BROMIDE ENANTIOMER WITH A PROLONGED DURATION OF ACTION | BOEHRINGER INGELHEIM KG (DE) | 1997-02-13 | — | — | WO | claimed |
| EP-0514415-A1 | NOVEL VEHICLE GAS MIXTURES AND THEIR USE IN MEDICAL PREPARATIONS | BOEHRINGER INGELHEIM KG (DE) | 1992-11-25 | — | — | EP | claimed |
| EP-0513099-A1 | NOVEL VEHICLE GASES AND THEIR USE IN MEDICAL PREPARATIONS | BOEHRINGER INGELHEIM KG (DE) | 1992-11-19 | — | — | EP | claimed |
| WO-1991011496-A1 | NOVEL VEHICLE GASES AND THEIR USE IN MEDICAL PREPARATIONS | BOEHRINGER INGELHEIM KG (DE) | 1991-08-08 | — | — | WO | claimed |
| WO-1991011495-A1 | NOVEL VEHICLE GAS MIXTURES AND THEIR USE IN MEDICAL PREPARATIONS | BOEHRINGER INGELHEIM KG (DE) | 1991-08-08 | — | — | WO | claimed |
| EP-0201732-A2 | Beta-2-mimetics of the 4-aminophenylethanolamine type for the prevention of peptic ulcers | BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) | 1986-11-20 | — | — | EP | claimed |
| EP-0057900-B1 | ANIMAL FEED ADDITIVE FOR IMPROVING GROWTH | Dr. Karl Thomae GmbH (DE) | 1985-05-08 | — | — | EP | claimed |
| EP-0008715-B1 | PHENYLETHANOLAMINES FOR USE IN COMBATTING INFLAMMATORY CONDITIONS | Dr. Karl Thomae GmbH (DE) | 1981-11-25 | — | — | EP | claimed |
| US-4214001-A | ANALGESICS, ANTISPASMODICS AND ANTIASTHMATICS | BOEHRINGER INGELHEIM GMBH (DE) | 1980-07-22 | — | — | US | claimed |
| EP-0008715-A1 | Phenylethanolamines for use in combatting inflammatory conditions | Dr. Karl Thomae GmbH (DE) | 1980-03-19 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120010179-A1 | Methods of using a thiazole derivative | ADRB2, NR3C2, ADRA2A | LMNA 3085/4885ADRB2 1/4885CYP2D6 562/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.