Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | PDE1A | P54750 | 1/20 | 0.33 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.33 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7370161 | 0.88 | LIPG (0.40) | HTR2ANUDT1L3MBTL1KCNH2 | |
| SCHEMBL3314980 | 0.85 | NUDT1 (0.41) | HCRTR2HTR2ANUDT1L3MBTL1HTR2C | |
| SCHEMBL23343780 | 0.82 | HTR2A (0.41) | HCRTR2HTR2ANUDT1L3MBTL1HTR2C | |
| SCHEMBL9111359 | 0.79 | NUDT1 (0.42) | HTR2ANUDT1L3MBTL1HTR2CKCNH2 | |
| SCHEMBL10918746 | 0.79 | ATP4A (0.48) | HTR2ANUDT1L3MBTL1HTR1A | |
| SCHEMBL2315461 | 0.78 | NUDT1 (0.41) | HCRTR2HTR2ANUDT1L3MBTL1HTR2C | |
| SCHEMBL325061 | 0.78 | NUDT1 (0.45) | HTR2ANUDT1HTR2CKCNH2 | |
| SCHEMBL325060 | 0.78 | NUDT1 (0.41) | HTR2ANUDT1L3MBTL1HTR2CKCNH2 | |
| SCHEMBL5308911 | 0.78 | NUDT1 (0.41) | HTR2ANUDT1L3MBTL1HTR2CKCNH2 | |
| SCHEMBL9934928 | 0.78 | NUDT1 (0.41) | HCRTR2HTR2ANUDT1L3MBTL1PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8778964-B2 | Hydroxy-substituted imidazo[1,2-a]-pyridinecarboxamides and their use | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2014-07-15 | — | — | US | disclosed |