SCHEMBL15870366

SCHEMBL15870366

NCCOCCOCCNC(=O)CCC(N)=O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 8/20 0.44
CA12 O43570 6/20 0.44
CA1 P00915 6/20 0.44
CA4 P22748 6/20 0.44
CA9 Q16790 6/20 0.44
CA14 Q9ULX7 6/20 0.44
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.35
ADORA3 P0DMS8 1/20 0.35
TSHR P16473 1/20 0.34
NPY1R P25929 1/20 0.34
NPY4R P50391 1/20 0.34
TLR2 O60603 1/20 0.33
ADRB2 P07550 1/20 0.33
HTR1A P08908 1/20 0.33
ALDH1A1 P00352 1/20 0.32
HDAC3 O15379 1/20 0.31
HDAC1 Q13547 1/20 0.31
NCF1 P14598 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19172671 0.93 CA2 (0.49) CA2CA12CA1CA4CA9
SCHEMBL24592016 0.89 CA2 (0.47) CA2CA12CA1CA4CA9
SCHEMBL26430827 0.87 CA2 (0.44) CA2CA12CA1CA4CA9
SCHEMBL14575431 0.87 CA2 (0.44) CA2CA12CA1CA4CA9
SCHEMBL21415394 0.87 CA2 (0.44) CA2CA12CA1CA4CA9
SCHEMBL19594069 0.87 CA2 (0.44) CA2CA12CA1CA4CA9
SCHEMBL14197469 0.87 CA2 (0.44) CA2CA12CA1CA4CA9
SCHEMBL20904578 0.87 CA2 (0.44) CA2CA12CA1CA4CA9
SCHEMBL23157585 0.86 CA2 (0.44) CA2CA12CA1CA4CA9
SCHEMBL23157519 0.86 CA2 (0.44) CA2CA12CA1CA4CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12157778-B2 Peptides for activation of cell signaling in osteoprogenitor cells THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-12-03 US disclosed
US-20220168433-A1 PROGRAMMABLE POLYMERIC DRUGS Sony Group Corporation (JP) 2022-06-02 US disclosed
US-20220168435-A1 PROGRAMMABLE POLYMERIC DRUGS SONY CORPORATION (JP) 2022-06-02 US disclosed
US-20220160887-A1 PROGRAMMABLE POLYMERIC DRUGS Sony Group Corporation (JP) 2022-05-26 US disclosed
US-20210395302-A1 PEPTIDES FOR ACTIVATION OF CELL SIGNALING IN OSTEOPROGENITOR CELLS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2021-12-23 US disclosed
WO-2021228939-A1 FLUOROGENIC DIMER COMPOUND, USEFUL AS A PROBE FOR DETECTION OF ENDOGENOUS RECEPTORS UNIVERSITE DE STRASBOURG (FR) 2021-11-18 WO disclosed
EP-3823630-A1 PEPTIDES FOR ACTIVATION OF CELL SIGNALING IN OSTEOPROGENITOR CELLS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2021-05-26 EP disclosed
CN-112672747-A Peptides for activating cell signalling in osteoprogenitor cells 加利福尼亚大学董事会 2021-04-16 CN disclosed
WO-2020018941-A1 PEPTIDES FOR ACTIVATION OF CELL SIGNALING IN OSTEOPROGENITOR CELLS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2020-01-23 WO disclosed
US-20140193342-A1 ENZYME DIRECTED ASSEMBLY OF PARTICLE THERANOSTICS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2014-07-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210395302-A1 PEPTIDES FOR ACTIVATION OF CELL SIGNALING IN OSTEOPROGENITOR CELLS ITGB4, ITGA4, ITGB1 CA2 3288/4885CA12 3008/4885CA1 2602/4885
US-20220160887-A1 PROGRAMMABLE POLYMERIC DRUGS CHRM1, NCL, PBRM1 CA2 2294/4885CA12 2584/4885CA1 1348/4885
US-20220168433-A1 PROGRAMMABLE POLYMERIC DRUGS CHRM1, PBRM1, CHRM2 CA2 2260/4885CA12 2163/4885CA1 1378/4885
US-20220168435-A1 PROGRAMMABLE POLYMERIC DRUGS CHRM1, PBRM1, CHRM2 CA2 2274/4885CA12 2169/4885CA1 1380/4885
US-12157778-B2 Peptides for activation of cell signaling in osteoprogenitor cells ITGB4, ITGA4, ITGB1 CA2 3288/4885CA12 3008/4885CA1 2602/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.