Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 17/20 | 0.57 |
| ▸ | PSMB1 | P20618 | 11/20 | 0.54 |
| ▸ | PSMB2 | P49721 | 10/20 | 0.54 |
| ▸ | PSMB8 | P28062 | 10/20 | 0.54 |
| ▸ | PSMB9 | P28065 | 10/20 | 0.54 |
| ▸ | PSMB6 | P28072 | 10/20 | 0.54 |
| ▸ | PSMB10 | P40306 | 10/20 | 0.54 |
| ▸ | LONP1 | P36776 | 9/20 | 0.54 |
| ▸ | PSMB11 | A5LHX3 | 9/20 | 0.54 |
| ▸ | PSMA7 | O14818 | 9/20 | 0.54 |
| ▸ | PSMA1 | P25786 | 9/20 | 0.54 |
| ▸ | PSMA2 | P25787 | 9/20 | 0.54 |
| ▸ | PSMA3 | P25788 | 9/20 | 0.54 |
| ▸ | PSMA4 | P25789 | 9/20 | 0.54 |
| ▸ | PSMA5 | P28066 | 9/20 | 0.54 |
| ▸ | PSMB4 | P28070 | 9/20 | 0.54 |
| ▸ | PSMB3 | P49720 | 9/20 | 0.54 |
| ▸ | PSMA6 | P60900 | 9/20 | 0.54 |
| ▸ | PSMA8 | Q8TAA3 | 9/20 | 0.54 |
| ▸ | PSMB7 | Q99436 | 9/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18330636 | 0.89 | PSMB5 (0.59) | PSMB5PSMB1PSMB2PSMB8PSMB9 | |
| SCHEMBL15267521 | 0.89 | PSMB5 (0.63) | PSMB5PSMB1PSMB2PSMB8PSMB9 | |
| SCHEMBL21706356 | 0.88 | PSMB5 (0.56) | PSMB5PSMB1PSMB2PSMB8PSMB9 | |
| SCHEMBL18848503 | 0.88 | PSMB5 (0.55) | PSMB5PSMB1PSMB2PSMB8PSMB9 | |
| SCHEMBL24637970 | 0.87 | PSMB5 (0.55) | PSMB5PSMB1PSMB2PSMB8PSMB9 | |
| SCHEMBL20549905 | 0.87 | PSMB5 (0.55) | PSMB5PSMB1PSMB2PSMB8PSMB9 | |
| SCHEMBL20549712 | 0.87 | PSMB5 (0.55) | PSMB5PSMB1PSMB2PSMB8PSMB9 | |
| SCHEMBL18848525 | 0.87 | PSMB5 (0.55) | PSMB5PSMB1PSMB2PSMB8PSMB9 | |
| SCHEMBL18848516 | 0.86 | PSMB5 (0.53) | PSMB5PSMB1PSMB2PSMB8PSMB9 | |
| SCHEMBL18316405 | 0.86 | PSMB5 (0.61) | PSMB5PSMB1PSMB2PSMB8PSMB9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200323889-A1 | CYCLODEXTRIN-BASED POLYMERS FOR THERAPEUTIC DELIVERY | CERULEAN PHARMA INC. | 2020-10-15 | — | — | US | disclosed |
| US-20180193486-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF AUTOIMMUNE AND OTHER DISEASE | CERULEAN PHARMA INC. | 2018-07-12 | — | — | US | disclosed |
| US-20140193510-A1 | Polymer-Agent Conjugates, Particles, Compositions, and Related Methods of Use | CERULEAN PHARMA INC. (US) | 2014-07-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180193486-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF AUTOIMMUNE AND OTHER DISEASE | PHOSPHO1, SGMS1, SGMS2 | PSMB5 1149/4885PSMB1 1846/4885PSMB2 1429/4885 |
| US-20200323889-A1 | CYCLODEXTRIN-BASED POLYMERS FOR THERAPEUTIC DELIVERY | PSMG3, COPB1, PSMA6 | PSMB5 18/4885PSMB1 6/4885PSMB2 16/4885 |
| US-20140193510-A1 | Polymer-Agent Conjugates, Particles, Compositions, and Related Methods of Use | LPXN, POLI, BRCA1 | PSMB5 1016/4885PSMB1 1551/4885PSMB2 841/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.