Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.67 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.67 |
| ▸ | HTR1A | P08908 | 1/20 | 0.67 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.67 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.67 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.67 |
| ▸ | DRD1 | P21728 | 1/20 | 0.67 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | BLM | P54132 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1587314 | 1.00 | CYP1A2 (0.67) | CYP1A2ADRB2ADRB1CYP3A4HTR1A | |
| SCHEMBL11528671 | 0.88 | TDP1 (0.69) | CYP1A2ADRB2ADRB1CYP3A4HTR1A | |
| SCHEMBL10749123 | 0.87 | TDP1 (0.67) | CYP1A2ADRB2ADRB1CYP3A4HTR1A | |
| SCHEMBL18908562 | 0.87 | CYP1A2 (0.71) | CYP1A2ADRB2ADRB1CYP3A4HTR1A | |
| SCHEMBL12648664 | 0.87 | TDP1 (0.67) | CYP1A2ADRB2ADRB1CYP3A4HTR1A | |
| SCHEMBL30673515 | 0.84 | CYP1A2 (0.67) | CYP1A2ADRB2ADRB1CYP3A4HTR1A | |
| SCHEMBL13149011 | 0.84 | CYP1A2 (0.77) | CYP1A2ADRB2ADRB1CYP3A4HTR1A | |
| SCHEMBL10983705 | 0.82 | CYP1A2 (0.74) | CYP1A2ADRB2ADRB1CYP3A4HTR1A | |
| SCHEMBL11193337 | 0.82 | CYP1A2 (0.74) | CYP1A2ADRB2ADRB1CYP3A4HTR1A | |
| SCHEMBL11755634 | 0.82 | CYP1A2 (0.74) | CYP1A2ADRB2ADRB1CYP3A4HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110092507-A1 | Process for preparing R-(+)-3-morpholino-4-(3- tert-butylamino-2-hydroxypropoxy)-1,2,5-thiadiazole | SYN-TECH CHEM. & PHARM. CO., LTD. (TW) | 2011-04-21 | — | — | US | disclosed |
| US-20110092507-A1 | Process for preparing R-(+)-3-morpholino-4-(3- tert-butylamino-2-hydroxypropoxy)-1,2,5-thiadiazole | SYN-TECH CHEM. & PHARM. CO., LTD. (TW) | 2011-04-21 | — | — | US | disclosed |
| US-20110092507-A1 | Process for preparing R-(+)-3-morpholino-4-(3- tert-butylamino-2-hydroxypropoxy)-1,2,5-thiadiazole | SYN-TECH CHEM. & PHARM. CO., LTD. (TW) | 2011-04-21 | — | — | US | disclosed |
| EP-0283147-B1 | Labile ketone derivatives of 3-substituted-1-alkylamino-2-propanols and their use as beta-adrenergic blockers | UNIV FLORIDA (US) | 1994-05-11 | — | — | EP | disclosed |
| US-5017618-A | Treatment Of Glaucoma | UNIVERSITY OF FLORIDA (US) | 1991-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110092507-A1 | Process for preparing R-(+)-3-morpholino-4-(3- tert-butylamino-2-hydroxypropoxy)-1,2,5-thiadiazole | KCNH3, KCNN3, KCNH2 | CYP1A2 412/4885ADRB2 45/4885ADRB1 29/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.