Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 4/20 | 0.51 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28670572 | 0.82 | ERN1 (0.47) | ALDH1A1TDP1GSTP1HDAC4HDAC2 | |
| SCHEMBL7814268 | 0.80 | ALDH1A1 (0.64) | ALDH1A1TDP1TSHRCYP3A4HPRT1 | |
| SCHEMBL18201473 | 0.78 | CYP3A4 (0.56) | ALDH1A1TDP1TSHRGSTP1CYP3A4 | |
| SCHEMBL11847292 | 0.78 | ALDH1A1 (0.78) | ALDH1A1TDP1TSHRCYP3A4PKM | |
| SCHEMBL27947322 | 0.76 | ALDH1A1 (0.58) | ALDH1A1TDP1TSHRCYP3A4HPRT1 | |
| SCHEMBL28950035 | 0.76 | ALDH1A1 (0.58) | ALDH1A1TDP1TSHRCYP3A4HPRT1 | |
| SCHEMBL3155647 | 0.76 | CTSD (0.59) | ALDH1A1TDP1TSHRGSTP1CYP3A4 | |
| SCHEMBL15876114 | 0.76 | HSD17B10 (0.51) | ALDH1A1TDP1TSHRHPRT1LMNA | |
| SCHEMBL14979389 | 0.76 | ALDH1A1 (0.61) | ALDH1A1TDP1TSHRGSTP1CYP3A4 | |
| SCHEMBL2557207 | 0.75 | GSTP1 (0.52) | ALDH1A1TDP1TSHRGSTP1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014111493-A1 | SUBSTITUTED BENZIMIDAZOLYL PHOSPHINE COMPOUNDS AND A METHOD FOR DECARBOXYLATING CARBON-CARBON LINKING | SALTIGO GMBH (DE) | 2014-07-24 | — | — | WO | disclosed |
| WO-2014111493-A1 | SUBSTITUTED BENZIMIDAZOLYL PHOSPHINE COMPOUNDS AND A METHOD FOR DECARBOXYLATING CARBON-CARBON LINKING | SALTIGO GMBH (DE) | 2014-07-24 | — | — | WO | disclosed |
| EP-2757106-A1 | Substituted benzimidazole phosphine compounds and a method for decarboxylating carbon-carbon bond | Saltigo GmbH (DE) | 2014-07-23 | — | — | EP | disclosed |
| EP-2757106-A1 | Substituted benzimidazole phosphine compounds and a method for decarboxylating carbon-carbon bond | Saltigo GmbH (DE) | 2014-07-23 | — | — | EP | disclosed |