Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 1/20 | 0.59 |
| ▸ | BACE1 | P56817 | 1/20 | 0.59 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.57 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | LCK | P06239 | 1/20 | 0.51 |
| ▸ | KDR | P35968 | 1/20 | 0.51 |
| ▸ | JAK3 | P52333 | 1/20 | 0.51 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.50 |
| ▸ | ESR1 | P03372 | 2/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11085362 | 0.94 | CTSD (0.57) | CTSDBACE1GSTP1TRPA1HDAC4 | |
| SCHEMBL2557207 | 0.86 | GSTP1 (0.52) | CTSDBACE1GSTP1TRPA1HDAC4 | |
| SCHEMBL14417256 | 0.84 | ESR2 (0.73) | CTSDBACE1TRPA1ESR2ESR1 | |
| Ammonia Solution, Strong SCHEMBL28921888 | 0.84 | GSTP1 (0.50) | CTSDBACE1GSTP1TRPA1HDAC4 | |
| SCHEMBL28841094 | 0.84 | CYP11B2 (0.59) | CTSDBACE1GSTP1TRPA1SLC6A2 | |
| SCHEMBL28508645 | 0.84 | GSTP1 (0.70) | GSTP1HDAC4HDAC2HDAC8ESR2 | |
| SCHEMBL30491158 | 0.84 | GSTP1 (0.70) | GSTP1HDAC4HDAC2HDAC8ESR2 | |
| SCHEMBL23380242 | 0.83 | GSTP1 (0.48) | CTSDBACE1GSTP1TRPA1HDAC4 | |
| SCHEMBL12344996 | 0.83 | CYP2A6 (0.50) | CTSDBACE1GSTP1TRPA1HDAC4 | |
| SCHEMBL19440078 | 0.83 | CYP11B2 (0.62) | CTSDBACE1GSTP1TRPA1CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210070782-A1 | METHOD FOR SYNTHESIZING BORONATE ESTER COMPOUND, SODIUM SALT OF BORONATE ESTER COMPOUND, AND METHOD FOR SYNTHESIZING THE SAME | KOBELCO ECO-SOLUTIONS CO., LTD. (JP) | 2021-03-11 | — | — | US | disclosed |
| EP-3741764-A1 | SYNTHESIS METHOD FOR BORONIC ACID ESTER COMPOUND, AND SODIUM SALT OF BORONIC ACID ESTER COMPOUND AND SYNTHESIS METHOD THEREFOR | Kobelco Eco-Solutions Co., Ltd (JP) | 2020-11-25 | — | — | EP | disclosed |
| US-9708351-B2 | Alkenes as alkyne equivalents in radical cascades terminated by fragmentations | The Florida State University Research Foundation, Inc. (US) | 2017-07-18 | — | — | US | disclosed |
| US-20160347778-A1 | ALKENES AS ALKYNE EQUIVALENTS IN RADICAL CASCADES TERMINATED BY FRAGMENTATIONS | The Florida State University Research Foundation, Inc. | 2016-12-01 | — | — | US | disclosed |
| EP-1270614-B1 | Copolymers containing propylene and alpha-olefin comonomer | BASELL POLYOLEFINE GMBH (DE) | 2010-01-27 | — | — | EP | disclosed |
| US-6924301-B1 | Composition for treating or preventing arrhythmia | SHIONOGI & CO., LTD. (JP) | 2005-08-02 | — | — | US | disclosed |
| US-6787618-B1 | TRANSPARENT, STIFF MOLDING MATERIALS; IMPACT TOUGHNESS; FOOD PACKAGING | BASELL POLYPROPYLEN GMBH (DE) | 2004-09-07 | — | — | US | disclosed |
| EP-0776913-B1 | High molecular weight copolymers | BASELL POLYOLEFINE GMBH (DE) | 2004-02-04 | — | — | EP | disclosed |
| EP-0976748-B1 | PYRROLIDINE DERIVATIVES HAVING PHOSPHOLIPASE A2 INHIBITORY ACTIVITY | SHIONOGI & CO (JP) | 2003-12-03 | — | — | EP | disclosed |
| EP-1270614-A2 | Copolymers containing propylene and alpha-olefin comonomer | Basell Polyolefine GmbH (DE) | 2003-01-02 | — | — | EP | disclosed |
| US-6051727-A | A POLYMERIZATION CATALYST FOR POLYOLEFINS OF HIGH MOLECULAR WEIGHT, OF PARTICULAR IMPORTANCE FOR THE PRODUCTION OF FILMS, SHEETS OR LARGE HOLLOW ARTICLES OR MOLDINGS SUCH AS PIPES | TARGOR GMBH (DE) | 2000-04-18 | — | — | US | disclosed |
| EP-0976748-A1 | PYRROLIDINE DERIVATIVES HAVING PHOSPHOLIPASE A2 INHIBITORY ACTIVITY | SHIONOGI & CO., LTD. (JP) | 2000-02-02 | — | — | EP | disclosed |
| US-5840644-A | OLEFIN POLYMERIZATION CATALYSTS | TARGOR GMBH (DE) | 1998-11-24 | — | — | US | disclosed |
| US-5786432-A | POLYMERIZING OR COPOLYMERIZING OLEFIN IN PRESENCE OF TRANSITION METAL METALLOCENE CATALYST AND COCATALYST | TARGOR GMBH (DE) | 1998-07-28 | — | — | US | disclosed |
| US-5770753-A | ADDITION POLYMERIZATION CATALYST | TARGOR GMBH (DE) | 1998-06-23 | — | — | US | disclosed |
| EP-0576970-B1 | Metallocenes with arylsubstituted indenyl-derivatives as ligands, process for their preparation and their use as catalysts | HOECHST AG (DE) | 1998-01-14 | — | — | EP | disclosed |
| EP-0790076-A2 | Catalysts containing metallocenes with arylsubstituted indenyl derivatives as ligands, process and intermediates for the preparation of these metallocenes and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-08-20 | — | — | EP | disclosed |
| EP-0776913-A2 | High molecular weight copolymers | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-06-04 | — | — | EP | disclosed |
| EP-0576970-A1 | Metallocenes with arylsubstituted indenyl-derivatives as ligands, process for their preparation and their use as catalysts | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-01-05 | — | — | EP | disclosed |
| US-5153226-A | Administering as anticholesterol agents, for atherosclerosis | WARNER-LAMBERT COMPANY (US) | 1992-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210070782-A1 | METHOD FOR SYNTHESIZING BORONATE ESTER COMPOUND, SODIUM SALT OF BORONATE ESTER COMPOUND, AND METHOD FOR SYNTHESIZING THE SAME | BRSK1, BRSK2, BRI3BP | CTSD 3606/4885BACE1 4119/4885GSTP1 4708/4885 |
| US-20160347778-A1 | ALKENES AS ALKYNE EQUIVALENTS IN RADICAL CASCADES TERMINATED BY FRAGMENTATIONS | AOC3, OR51E2, AOC2 | CTSD 2899/4885BACE1 445/4885GSTP1 1292/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.