Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | CA9 | Q16790 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10873331 | 0.81 | ESR2 (0.44) | KDM4EALDH1A1HPGDKMT2ALMNA | |
| SCHEMBL5160745 | 0.81 | HSD17B10 (0.44) | KDM4ECA12CA9NPC1HTT | |
| SCHEMBL18920885 | 0.76 | CYP2C9 (0.45) | L3MBTL1KDM4ECA12CA9RAB9A | |
| SCHEMBL15619119 | 0.74 | KCNH2 (0.56) | L3MBTL1KCNH2RAB9ANPC1HTT | |
| SCHEMBL1860716 | 0.73 | MAOB (0.43) | KDM4EHTTALDH1A1HPGDLMNA | |
| SCHEMBL442779 | 0.73 | MCL1 (0.60) | L3MBTL1KDM4EKCNH2RAB9ANPC1 | |
| Carbamic Acid SCHEMBL27823881 | 0.71 | L3MBTL1 (0.49) | L3MBTL1KDM4EKCNH2CA12CA2 | |
| Acetic Acid SCHEMBL15653002 | 0.71 | KDM4E (0.66) | KDM4ECA12CA9RAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL9789912 | 0.71 | MCL1 (0.58) | L3MBTL1KDM4EKCNH2RAB9ANPC1 | |
| SCHEMBL10604086 | 0.70 | HSD17B10 (0.44) | KDM4ECA12CA2CA9NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014111493-A1 | SUBSTITUTED BENZIMIDAZOLYL PHOSPHINE COMPOUNDS AND A METHOD FOR DECARBOXYLATING CARBON-CARBON LINKING | SALTIGO GMBH (DE) | 2014-07-24 | — | — | WO | disclosed |
| EP-2757106-A1 | Substituted benzimidazole phosphine compounds and a method for decarboxylating carbon-carbon bond | Saltigo GmbH (DE) | 2014-07-23 | — | — | EP | disclosed |