Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 11/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3476282 | 0.80 | KDM4E (0.67) | SMN1; SMN2ALDH1A1LMNAKDM4ERAB9A | |
| SCHEMBL15876919 | 0.73 | NSD2 (0.45) | SMN1; SMN2ALDH1A1LMNAKDM4ERAB9A | |
| SCHEMBL11427962 | 0.70 | KDM4E (0.72) | SMN1; SMN2ALDH1A1LMNAKDM4ERAB9A | |
| SCHEMBL27108411 | 0.69 | MAOA (0.39) | SMN1; SMN2ALDH1A1LMNAKDM4ERAB9A | |
| SCHEMBL12335783 | 0.69 | KDM4E (0.36) | SMN1; SMN2ALDH1A1LMNAKDM4ERAB9A | |
| SCHEMBL9570209 | 0.66 | PDE10A (0.34) | SMN1; SMN2ALDH1A1LMNAKDM4ERAB9A | |
| SCHEMBL2961962 | 0.66 | KDM4E (0.55) | SMN1; SMN2ALDH1A1KDM4EPDE10AHPGD | |
| SCHEMBL9597058 | 0.66 | PDE10A (0.34) | SMN1; SMN2ALDH1A1KDM4ERAB9ANPC1 | |
| SCHEMBL2942757 | 0.65 | KDM4E (0.54) | ALDH1A1KDM4EPDE10AHPGDPOLB | |
| SCHEMBL29958329 | 0.65 | SMN1; SMN2 (0.42) | SMN1; SMN2ALDH1A1LMNAKDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140206696-A1 | (1-AZINONE)-SUBSTITUTED PYRIDOINDOLES | ALBANY MOLECULAR RESEARCH, INC. (US) | 2014-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140206696-A1 | (1-AZINONE)-SUBSTITUTED PYRIDOINDOLES | NR3C2, NR2E3, NR0B1 | SMN1; SMN2 2052/4885ALDH1A1 2106/4885LMNA 1957/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.