Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 7/20 | 0.55 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.41 |
| ▸ | MET | P08581 | 10/20 | 0.40 |
| ▸ | KDR | P35968 | 3/20 | 0.39 |
| ▸ | MST1R | Q04912 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15878762 | 0.81 | AXL (0.65) | AXLFGFR2METKDRMST1R | |
| SCHEMBL15878763 | 0.78 | AXL (0.68) | AXLFGFR2METKDRMST1R | |
| SCHEMBL166914 | 0.77 | AXL (0.67) | AXLFGFR2METKDRMST1R | |
| Hydrochloric Acid SCHEMBL30388215 | 0.76 | AXL (0.66) | AXLFGFR2METKDRMST1R | |
| Hydrochloric Acid SCHEMBL21776567 | 0.76 | AXL (0.66) | AXLFGFR2METKDRMST1R | |
| SCHEMBL17035605 | 0.76 | AXL (0.66) | AXLFGFR2METKDRMST1R | |
| SCHEMBL371860 | 0.76 | AXL (0.53) | AXLFGFR2METKDRMST1R | |
| SCHEMBL17035604 | 0.75 | AXL (0.64) | AXLFGFR2METKDRMST1R | |
| SCHEMBL28424820 | 0.75 | EGFR (0.58) | KDRFLT3 | |
| SCHEMBL22394465 | 0.73 | EGFR (0.61) | AXLMETKDRFLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9562060-B2 | Heterocyclic pyridone compound, and intermediate, preparation method and use thereof | SHANGHAI HUILUN LIFE SCIENCE & TECHNOLOGY CO., LTD (CN) | 2017-02-07 | — | — | US | disclosed |
| US-20140206679-A1 | HETEROCYCLIC PYRIDONE COMPOUND, AND INTERMEDIATE, PREPARATION METHOD AND USE THEREOF | SHANGHAI HUILUN LIFE SCIENCE & TECHNOLOGY CO., LTD (CN) | 2014-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140206679-A1 | HETEROCYCLIC PYRIDONE COMPOUND, AND INTERMEDIATE, PREPARATION METHOD AND USE THEREOF | MET, PDXK, FLT3 | AXL 22/4885FGFR2 291/4885MET 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.