SCHEMBL1587900

SCHEMBL1587900

COc1[c]ccc(-c2ccccc2OC)c1OC

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 1/20 0.42
CA12 O43570 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CA4 P22748 1/20 0.40
CA7 P43166 1/20 0.40
CA9 Q16790 1/20 0.40
CA14 Q9ULX7 1/20 0.40
ALDH1A1 P00352 5/20 0.40
HTR7 P34969 4/20 0.39
HSD17B10 Q99714 3/20 0.37
KDM4E B2RXH2 3/20 0.37
CYP3A4 P08684 2/20 0.37
CYP2C9 P11712 1/20 0.37
TSHR P16473 1/20 0.37
CYP2C19 P33261 1/20 0.37
HPGD P15428 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
MAPT P10636 1/20 0.36
HDAC4 P56524 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10535184 0.80 APP (0.46) APPCA12CA1CA2CA4
SCHEMBL4439979 0.79 ALDH1A1 (0.42) APPCA12CA1CA2CA4
SCHEMBL2373679 0.79 CYP1A1 (0.46) CA12CA1CA2CA7CA9
SCHEMBL7823588 0.79 PDE4B (0.40) ALDH1A1KDM4ECYP3A4TSHRSMN1; SMN2
SCHEMBL11100996 0.77 APP (0.47) APPCA12CA1CA2CA4
SCHEMBL7466427 0.76 APP (0.42) APPCA12CA1CA2CA4
SCHEMBL77640 0.75 CA9 (0.35) CA12CA1CA2CA4CA7
SCHEMBL2372581 0.74 APP (0.47) APPCA12CA1CA2CA4
SCHEMBL29788337 0.74 CA1 (0.71) APPCA12CA1CA2CA4
SCHEMBL29429633 0.74 CA1 (0.71) APPCA12CA1CA2CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1546089-A2 ARYL AND HETEROARYL COMPOUNDS AND METHODS TO MODULATE COAGULATION TransTech Pharma Inc. (US) 2005-06-29 EP claimed
WO-2004014844-A2 ARYL AND HETEROARYL COMPOUNDS AND METHODS TO MODULATE COAGULATION TRANSTECH PHARMA, INC. (US) 2004-02-19 WO claimed
US-20140287250-A1 COLOR STABILIZATION OF CORK AND COLORED WOODS BY THE COMBINED USE OF INORGANIC AND ORGANIC UV-ABSORBERS BASF SE (DE) 2014-09-25 US disclosed
US-20120328893-A1 COLOR STABILIZATION OF CORK AND COLORED WOODS BY THE COMBINED USE OF INORGANIC AND ORGANIC UV-ABSORBERS SCHALLER CHRISTIAN MARCUS (CH) 2012-12-27 US disclosed
EP-1979406-B1 STABILIZER COMPOSITION FOR POLYMERS BASF SE (DE) 2012-10-24 EP disclosed
US-8173728-B2 Stabilizer composition for polymers BASF SE (DE) 2012-05-08 US disclosed
US-20110092632-A1 POROUS INORGANIC MATERIALS CONTAINING POLYMER ADDITIVES BRAND FABIEN JEAN 2011-04-21 US disclosed
US-20100222471-A1 Stabilizer Composition for Polymers CIBA CORPORATION 2010-09-02 US disclosed
US-7687554-B2 Water based concentrated product forms of light stabilizers made by a heterophase polymerization technique CIBA SPECIALTY CHEMICALS CORPORATION (US) 2010-03-30 US disclosed
US-20090258240-A1 Color Stabilization of Cork and Colored Woods by the Combined Use of Inorganic and Organic UV-Absorbers BASF SE (DE) 2009-10-15 US disclosed
EP-1954457-B1 COLOR STABILIZATION OF CORK AND COLORED WOODS BY THE COMBINED USE OF INORGANIC AND ORGANIC UV-ABSORBERS CIBA HOLDING INC (CH) 2009-04-15 EP disclosed
WO-2006008240-A1 POROUS INORGANIC MATERIALS CONTAINING POLYMER ADDITIVES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2006-01-26 WO disclosed
US-6878761-B2 Synergistic combinations of UV absorbers for pigmented polyolefins CIBA SPECIALTY CHEMICALS CORP. (US) 2005-04-12 US disclosed
WO-2005023878-A1 WATER BASED CONCENTRATED PRODUCT FORMS OF LIGHT STABILIZERS MADE BY A HETEROPHASE POLYMERIZATION TECHNIQUE CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2005-03-17 WO disclosed
US-20040087446-A1 Composition and process for enhancing bio-mass production in greenhouses CIBA SPECIALTY CHEMICALS CORP. 2004-05-06 US disclosed
EP-1413599-A1 Composition and process for enhancing biomass production in greenhouses Ciba SC Holding AG (CH) 2004-04-28 EP disclosed
US-20040030009-A1 Synergistic combinations of UV absorbers for pigmented polyolefins CIBA SPECIALTY CHEMICALS CORP. 2004-02-12 US disclosed
EP-1342748-A1 Synergistic combinations of UV Absorbers for pigmented polyolefins Ciba SC Holding AG (CH) 2003-09-10 EP disclosed
US-5811452-A ADMINISTERING WITH PACLITAXEL OR DOXORUBICIN THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) 1998-09-22 US disclosed
US-4220708-A Photochromic compounds GEC-MARONI LIMITED (GB) 1980-09-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040087446-A1 Composition and process for enhancing bio-mass production in greenhouses BOLA2; BOLA2B, BROX, PGD APP 4323/4885CA12 2853/4885CA1 1477/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.