Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 11/20 | 0.39 |
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1665578 | 0.78 | DPP4 (0.36) | DPP4 | |
| SCHEMBL29868601 | 0.78 | DPP4 (0.36) | DPP4 | |
| SCHEMBL15879781 | 0.74 | P2RX7 (0.35) | RIPK1 | |
| SCHEMBL5907241 | 0.60 | HRH3 (0.48) | — | |
| SCHEMBL20499550 | 0.59 | NAMPT (0.37) | — | |
| SCHEMBL31010095 | 0.58 | HRH3 (0.52) | GAA | |
| SCHEMBL4574170 | 0.58 | ATM (0.37) | RIPK1 | |
| SCHEMBL2334972 | 0.58 | HPGD (0.39) | DPP4GAA | |
| SCHEMBL21451943 | 0.57 | TLR4 (0.41) | RIPK1 | |
| SCHEMBL18097762 | 0.57 | SCN9A (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140206667-A1 | METHODS AND COMPOSITIONS FOR TREATING SCHIZOPHRENIA | THE JOHNS HOPKINS UNIVERSITY | 2014-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140206667-A1 | METHODS AND COMPOSITIONS FOR TREATING SCHIZOPHRENIA | RAB2A, SYNGR2, GRIN2A | ROCK2 271/4885DPP4 3101/4885RIPK1 3450/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.