Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 12/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.57 |
| ▸ | HPGD | P15428 | 8/20 | 0.57 |
| ▸ | MEN1 | O00255 | 7/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.57 |
| ▸ | RAB9A | P51151 | 4/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 8/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.56 |
| ▸ | HTT | P42858 | 3/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.56 |
| ▸ | PPARG | P37231 | 2/20 | 0.56 |
| ▸ | NCOA2 | Q15596 | 2/20 | 0.56 |
| ▸ | NCOA1 | Q15788 | 2/20 | 0.56 |
| ▸ | NCOA3 | Q9Y6Q9 | 2/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15881215 | 0.83 | ALDH1A1 (0.64) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL13866406 | 0.77 | ALDH1A1 (0.53) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL21807638 | 0.75 | MAPT (0.72) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL14559557 | 0.74 | ALDH1A1 (0.64) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL4861625 | 0.73 | ALDH1A1 (0.64) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL17706301 | 0.73 | ALDH1A1 (0.55) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL12471994 | 0.72 | MEN1 (0.49) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL12411184 | 0.72 | ALDH1A1 (0.49) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL12403886 | 0.72 | MAPT (0.49) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL19472829 | 0.71 | MAPT (0.69) | KDM4EALDH1A1HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2945625-A2 | ANTI-VIRAL COMPOUNDS | Kineta, Inc. (US) | 2015-11-25 | — | — | EP | disclosed |
| WO-2014113492-A2 | ANTI-VIRAL COMPOUNDS | Kineta, Inc. (US) | 2014-07-24 | — | — | WO | disclosed |
| WO-2014113492-A2 | ANTI-VIRAL COMPOUNDS | Kineta, Inc. (US) | 2014-07-24 | — | — | WO | disclosed |