SCHEMBL1588087

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1587102	0.85	HDAC1 (0.43)	HPGDALDH1A1HDAC1HDAC6HDAC4
	SCHEMBL12529433	0.81	RAB9A (0.47)	HPGDALDH1A1HDAC1HDAC6HDAC4
	SCHEMBL14625223	0.78	HPGD (0.41)	HPGDALDH1A1HDAC1HDAC6HDAC4
	SCHEMBL1587639	0.75	HPGD (0.72)	HPGDALDH1A1KDM4EPOLBMAPT
	SCHEMBL1587414	0.75	SMN1; SMN2 (0.42)	HPGDALDH1A1HDAC1HDAC6HDAC4
	SCHEMBL1587179	0.75	HSD17B10 (0.53)	ALDH1A1HDAC1HDAC6HDAC4HDAC3
	SCHEMBL276955	0.74	ALDH1A1 (0.58)	ALDH1A1HDAC1HDAC6HDAC4HDAC3
	SCHEMBL15577656	0.73	CTSK (0.41)	SLC8A1POLBMAPTTSHR
	SCHEMBL1587891	0.72	HPGD (0.72)	HPGDALDH1A1KDM4EPOLBRAB9A
	SCHEMBL12529550	0.72	ADORA2A (0.50)	HPGDALDH1A1KDM4EPOLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.