Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 9/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 8/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
| ▸ | DRD3 | P35462 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19820891 | 0.84 | RIPK1 (0.41) | CYP3A4ALDH1A1RIPK1CYP2C19HIF1A | |
| SCHEMBL19820873 | 0.81 | RIPK1 (0.41) | ALDH1A1RIPK1CYP2C19HIF1AMAPT | |
| SCHEMBL15979584 | 0.80 | ESR1 (0.40) | ESR1ESR2CYP3A4ALDH1A1RIPK1 | |
| SCHEMBL10608928 | 0.78 | ESR1 (0.46) | ESR1ESR2CYP3A4ALDH1A1CYP2C19 | |
| SCHEMBL22620371 | 0.76 | ESR1 (0.50) | ESR1ESR2CYP3A4CYP2C19MAPT | |
| SCHEMBL18139 | 0.76 | SHBG (0.53) | ESR1ESR2CYP3A4ALDH1A1CYP2C19 | |
| SCHEMBL15979585 | 0.76 | ESR1 (0.37) | ESR1ESR2CYP3A4ALDH1A1 | |
| SCHEMBL6157069 | 0.74 | SHBG (0.50) | ESR1ESR2CYP3A4ALDH1A1CYP2C19 | |
| SCHEMBL8373596 | 0.74 | ESR1 (0.55) | ESR1ESR2CYP3A4ALDH1A1RIPK1 | |
| SCHEMBL15854207 | 0.74 | ESR1 (0.55) | ESR1ESR2CYP3A4ALDH1A1RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9389511-B2 | Methods of making patterned structures of materials, patterned structures of materials, and methods of using same | CORNELL UNIVERSITY (US) | 2016-07-12 | — | — | US | disclosed |
| US-20140205818-A1 | METHODS OF MAKING PATTERNED STRUCTURES OF MATERIALS, PATTERNED STRUCTURES OF MATERIALS, AND METHODS OF USING SAME | Conrnell University (US) | 2014-07-24 | — | — | US | disclosed |