Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19820880 | 0.84 | SLC6A2 (0.40) | RIPK1GAASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6265732 | 0.82 | SLC6A2 (0.42) | RIPK1GAASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL15893491 | 0.81 | ESR1 (0.46) | RIPK1SLC6A2SLC6A3ALDH1A1MAPT | |
| SCHEMBL19820891 | 0.81 | RIPK1 (0.41) | RIPK1GAASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9586848 | 0.81 | SLC6A2 (0.41) | RIPK1GAASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL19820885 | 0.76 | CYP17A1 (0.36) | RIPK1SLC6A2SLC6A4SLC6A3MEN1 | |
| SCHEMBL19750813 | 0.75 | SLC6A2 (0.31) | RIPK1SLC6A2SLC6A4SLC6A3CYP2C19 | |
| SCHEMBL17703537 | 0.74 | CYP3A4 (0.40) | RIPK1GAASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL19267955 | 0.73 | RIPK1 (0.36) | RIPK1ALDH1A1CYP2C19HIF1ATAAR1 | |
| SCHEMBL3001776 | 0.72 | RIPK1 (0.49) | RIPK1SLC6A3ALDH1A1CYP2C19HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180031975-A1 | PATTERN TREATMENT METHODS | ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) | 2018-02-01 | — | — | US | disclosed |