SCHEMBL15899441

SCHEMBL15899441

CC(C)COC(C)C(c1ccccc1)c1ccccc1OC(=O)O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 1/20 0.36
CHRM1 P11229 1/20 0.36
ALDH1A1 P00352 4/20 0.36
TSHR P16473 2/20 0.36
POLB P06746 3/20 0.34
HTT P42858 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
KDM4E B2RXH2 4/20 0.34
MMP9 P14780 1/20 0.34
MMP8 P22894 1/20 0.34
HSD17B10 Q99714 3/20 0.33
FFAR1 O14842 1/20 0.33
GPR88 Q9GZN0 1/20 0.33
HPGD P15428 3/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
ESR1 P03372 1/20 0.33
ITGB3 P05106 1/20 0.33
ITGA2B P08514 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15899545 0.83 HPGD (0.38) ALDH1A1TSHRPOLBHTTNPSR1
SCHEMBL15899415 0.78 KDM4E (0.39) CHRM2CHRM1ALDH1A1TSHRPOLB
SCHEMBL15899456 0.76 TSHR (0.38) TSHRPOLBKDM4E
SCHEMBL8846909 0.75 TYR (0.42) ALDH1A1TSHRPOLBHTTNPSR1
SCHEMBL15899455 0.73 MEN1 (0.36) ALDH1A1TSHRPOLBHTTKDM4E
SCHEMBL15899436 0.73 HPGD (0.43) ALDH1A1TSHRPOLBHTTNPSR1
SCHEMBL9979219 0.72 TSHR (0.49) ALDH1A1TSHRL3MBTL1KDM4EHSD17B10
SCHEMBL25338308 0.70 L3MBTL1 (0.41) ALDH1A1TSHRPOLBHTTNPSR1
SCHEMBL15899293 0.70 ALDH1A1 (0.38) ALDH1A1TSHRPOLBHTTL3MBTL1
SCHEMBL9326599 0.70 ELANE (0.43) CHRM2CHRM1ALDH1A1TSHRPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2759552-B1 SOLID CATALYST COMPONENT FOR POLYMERIZATION OF OLEFIN, CATALYST FOR POLYMERIZATION OF OLEFIN, AND METHOD FOR PRODUCING OLEFIN POLYMER TOHO TITANIUM CO LTD (JP) 2016-02-10 EP disclosed
US-9243081-B2 Solid catalyst component for polymerization of olefin, catalyst for polymerization of olefin, and method for producing olefin polymer TOHO TITANIUM CO., LTD. (JP) 2016-01-26 US disclosed
US-20140343237-A1 SOLID CATALYST COMPONENT FOR POLYMERIZATION OF OLEFIN, CATALYST FOR POLYMERIZATION OF OLEFIN, AND METHOD FOR PRODUCING OLEFIN POLYMER TOHO TITANIUM CO., LTD. (JP) 2014-11-20 US disclosed
EP-2759552-A1 SOLID CATALYST COMPONENT FOR POLYMERIZATION OF OLEFIN, CATALYST FOR POLYMERIZATION OF OLEFIN, AND METHOD FOR PRODUCING OLEFIN POLYMER Toho Titanium CO., LTD. (JP) 2014-07-30 EP disclosed