Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15899448 | 0.83 | CYP2D6 (0.41) | HIF1AKCNN4CYP2C19KMT2AMAPT | |
| SCHEMBL8034194 | 0.81 | HIF1A (0.59) | CES1HIF1AKCNN4CYP2C19KMT2A | |
| SCHEMBL487150 | 0.79 | MAPK1 (0.43) | CES1HIF1AKCNN4CYP2C19ALDH1A1 | |
| SCHEMBL25338006 | 0.76 | CYP2C19 (0.45) | HIF1ACYP2C19KMT2AMAPTCHRM2 | |
| SCHEMBL6529360 | 0.75 | KMT2A (0.48) | CES1HIF1AKCNN4CYP2C19KMT2A | |
| SCHEMBL5832056 | 0.75 | ALDH1A1 (0.45) | CES1HIF1AKCNN4CYP2C19KMT2A | |
| SCHEMBL8040554 | 0.75 | HIF1A (0.44) | CES1HIF1AKCNN4CYP2C19KMT2A | |
| SCHEMBL5846764 | 0.75 | HIF1A (0.44) | CES1HIF1AKCNN4CYP2C19KMT2A | |
| SCHEMBL31187336 | 0.74 | SMN1; SMN2 (0.41) | KMT2AALDH1A1ALOX15MAPK1CYP2D6 | |
| SCHEMBL487220 | 0.74 | ALDH1A1 (0.46) | CES1HIF1AKCNN4CYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2759552-B1 | SOLID CATALYST COMPONENT FOR POLYMERIZATION OF OLEFIN, CATALYST FOR POLYMERIZATION OF OLEFIN, AND METHOD FOR PRODUCING OLEFIN POLYMER | TOHO TITANIUM CO LTD (JP) | 2016-02-10 | — | — | EP | disclosed |
| US-9243081-B2 | Solid catalyst component for polymerization of olefin, catalyst for polymerization of olefin, and method for producing olefin polymer | TOHO TITANIUM CO., LTD. (JP) | 2016-01-26 | — | — | US | disclosed |
| US-20140343237-A1 | SOLID CATALYST COMPONENT FOR POLYMERIZATION OF OLEFIN, CATALYST FOR POLYMERIZATION OF OLEFIN, AND METHOD FOR PRODUCING OLEFIN POLYMER | TOHO TITANIUM CO., LTD. (JP) | 2014-11-20 | — | — | US | disclosed |
| EP-2759552-A1 | SOLID CATALYST COMPONENT FOR POLYMERIZATION OF OLEFIN, CATALYST FOR POLYMERIZATION OF OLEFIN, AND METHOD FOR PRODUCING OLEFIN POLYMER | Toho Titanium CO., LTD. (JP) | 2014-07-30 | — | — | EP | disclosed |