Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10780734 | 0.83 | ALDH1A1 (0.52) | HIF1AMAPK1KCNN4CYP2C19CYP1A2 | |
| SCHEMBL5846764 | 0.83 | HIF1A (0.44) | HIF1AMAPK1KCNN4CYP2C19CYP1A2 | |
| SCHEMBL8034194 | 0.81 | HIF1A (0.59) | HIF1AMAPK1KCNN4CYP2C19CYP1A2 | |
| SCHEMBL11543298 | 0.80 | HIF1A (0.39) | HIF1AMAPK1KCNN4CYP2C19CYP1A2 | |
| SCHEMBL1325146 | 0.78 | HIF1A (0.41) | HIF1AMAPK1KCNN4CYP2C19CYP1A2 | |
| SCHEMBL8850502 | 0.77 | ELANE (0.41) | HIF1AMAPK1KCNN4CYP2C19TDP1 | |
| SCHEMBL15899461 | 0.75 | CES1 (0.43) | HIF1AMAPK1KCNN4CYP2C19TDP1 | |
| SCHEMBL10664452 | 0.75 | KIF11 (0.50) | HIF1AMAPK1MAPTALDH1A1CHRM2 | |
| SCHEMBL238594 | 0.73 | THRB (0.45) | HIF1AMAPK1KCNN4CYP2C19KMT2A | |
| SCHEMBL979085 | 0.72 | ALDH1A1 (0.41) | HIF1AMAPK1KCNN4CYP2C19CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6093792-A | COMPRISING FIRST COMONOMER UNITS DERIVED FROM LACTONES, LACTAMS, THIOLACTONES, OR NONFUNCTIONALIZED CYCLIC CARBONATES, AND SECOND COMONOMER UNITS DERIVED FROM FUNCTIONALIZED CYCLIC CARBONATES; MEDICAL USE | UNIVERSITY OF MASSACHUSETTS (US) | 2000-07-25 | — | — | US | disclosed |