Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 4/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL362442 | 0.77 | KMT2A (0.55) | KMT2AMAPTCYP2C19HIF1AKCNN4 | |
| SCHEMBL2813766 | 0.77 | MAPT (0.55) | KMT2AMAPTCYP2C19HIF1AKCNN4 | |
| SCHEMBL11249 | 0.76 | MAPT (0.42) | KMT2AMAPTCYP2C19HIF1ACES1 | |
| SCHEMBL5084151 | 0.76 | KMT2A (0.53) | KMT2AMAPTCYP2C19HIF1AKCNN4 | |
| Hydrochloric Acid SCHEMBL5789392 | 0.76 | MAPT (0.53) | KMT2AMAPTCYP2C19HIF1AKCNN4 | |
| SCHEMBL15899461 | 0.75 | CES1 (0.43) | KMT2AMAPTCYP2C19HIF1ACES1 | |
| SCHEMBL5832056 | 0.75 | ALDH1A1 (0.45) | KMT2AMAPTCYP2C19HIF1ACES1 | |
| SCHEMBL15397576 | 0.74 | MAPT (0.52) | KMT2AMAPTCYP2C19HIF1AKCNN4 | |
| SCHEMBL7385247 | 0.74 | MAPT (0.57) | KMT2AMAPTCYP2C19HIF1AKCNN4 | |
| SCHEMBL28275033 | 0.74 | MAPT (0.52) | KMT2AMAPTCYP2C19HIF1AKCNN4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050124652-A1 | Guanidino compounds | BOYCE RUSTUM (US) | 2005-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050124652-A1 | Guanidino compounds | MC4R, MC2R, GPR4 | KMT2A 3202/4885MAPT 2811/4885CYP2C19 2052/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.