Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 7/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | Q9HBH1 | 1/20 | 0.39 | |
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | HRH1 | P35367 | 2/20 | 0.37 |
| ▸ | KDM4A | O75164 | 6/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 6/20 | 0.37 |
| ▸ | KDM5A | P29375 | 1/20 | 0.37 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.37 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.37 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15900037 | 0.88 | FOLH1 (0.56) | FOLH1CA2MAPK1HTR2AHRH1 | |
| SCHEMBL8588142 | 0.82 | CA2 (0.63) | FOLH1CA2MAPK1HTR2AHRH1 | |
| Bromide SCHEMBL10570626 | 0.81 | DNM1 (0.50) | FOLH1CA2MAPK1HTR2AHRH1 | |
| SCHEMBL16263088 | 0.81 | FOLH1 (0.48) | FOLH1CA2MAPK1PDFHTR2A | |
| SCHEMBL29217 | 0.80 | FOLH1 (0.68) | FOLH1CA2MAPK1TDP1CPA1 | |
| SCHEMBL8590668 | 0.80 | CA2 (0.61) | FOLH1CA2MAPK1HTR2AHRH1 | |
| SCHEMBL27914221 | 0.79 | FOLH1 (0.47) | FOLH1CA2MAPK1PDFHTR2A | |
| SCHEMBL158836 | 0.78 | FOLH1 (0.65) | FOLH1CA2MAPK1TDP1CPA1 | |
| SCHEMBL30719576 | 0.78 | FOLH1 (0.65) | FOLH1CA2MAPK1TDP1CPA1 | |
| SCHEMBL352404 | 0.78 | FOLH1 (0.65) | FOLH1CA2MAPK1TDP1CPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2759547-B1 | PLATINUM COMPOUND HAVING AMINO- OR ALKYLAMINO-CONTAINING SUCCINIC ACID DERIVATIVES AS LEAVING GROUP, PREPARATION METHOD THEREFOR, AND USE THEREOF | BEIJING FSWELCOME TECH DEV CO LTD (CN) | 2017-01-18 | — | — | EP | claimed |
| CN-103649100-B | Platinum compound with leaving group of succinic acid derivative containing amino or alkylamino, preparation method and application thereof | 北京市丰硕维康技术开发有限责任公司 | 2016-06-22 | — | — | CN | claimed |
| EP-2759547-A1 | PLATINUM COMPOUND HAVING AMINO- OR ALKYLAMINO-CONTAINING SUCCINIC ACID DERIVATIVES AS LEAVING GROUP, PREPARATION METHOD THEREFOR, AND USE THEREOF | Beijing Fswelcome Technology Development Co., Ltd (CN) | 2014-07-30 | — | — | EP | claimed |
| CN-102993239-A | Platinum compound of succinic acid derivative with leaving group containing amino or alkylamino | CHEN XIAOPING | 2013-03-27 | — | — | CN | claimed |
| EP-2759547-B1 | PLATINUM COMPOUND HAVING AMINO- OR ALKYLAMINO-CONTAINING SUCCINIC ACID DERIVATIVES AS LEAVING GROUP, PREPARATION METHOD THEREFOR, AND USE THEREOF | BEIJING FSWELCOME TECH DEV CO LTD (CN) | 2017-01-18 | — | — | EP | disclosed |
| CN-103649100-B | Platinum compound with leaving group of succinic acid derivative containing amino or alkylamino, preparation method and application thereof | 北京市丰硕维康技术开发有限责任公司 | 2016-06-22 | — | — | CN | disclosed |
| US-9175024-B2 | Platinum compound having amino or alkylamino-containing succinic acid derivatives as leaving group, preparation method thereof, and use thereof | BEIJING FSWELCOME TECHNOLOGY DEVELOPMENT CO., LTD. (CN) | 2015-11-03 | — | — | US | disclosed |
| US-20140349985-A1 | PLATINUM COMPOUND HAVING AMINO OR ALKYLAMINO-CONTAINING SUCCINIC ACID DERIVATIVES AS LEAVING GROUP, PREPARTION METHOD THEREOF, AND USE THEREOF | BEIJING SHOWBY PHARMACEUTICAL CO., LTD. (CN) | 2014-11-27 | — | — | US | disclosed |
| EP-2759547-A1 | PLATINUM COMPOUND HAVING AMINO- OR ALKYLAMINO-CONTAINING SUCCINIC ACID DERIVATIVES AS LEAVING GROUP, PREPARATION METHOD THEREFOR, AND USE THEREOF | Beijing Fswelcome Technology Development Co., Ltd (CN) | 2014-07-30 | — | — | EP | disclosed |
| CN-102993239-A | Platinum compound of succinic acid derivative with leaving group containing amino or alkylamino | CHEN XIAOPING | 2013-03-27 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140349985-A1 | PLATINUM COMPOUND HAVING AMINO OR ALKYLAMINO-CONTAINING SUCCINIC ACID DERIVATIVES AS LEAVING GROUP, PREPARTION METHOD THEREOF, AND USE THEREOF | SLC7A5, SLC43A1, SLC7A1 | FOLH1 104/4885CA2 1746/4885MAPK1 3120/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.