Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | NAAA | Q02083 | 1/20 | 0.31 |
| ▸ | RAD52 | P43351 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25426 | 0.85 | TSHR (0.79) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL5144090 | 0.85 | TSHR (0.79) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL230028 | 0.85 | TSHR (0.61) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL22554429 | 0.83 | TSHR (0.83) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL22554413 | 0.83 | TSHR (0.83) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL22554423 | 0.83 | TSHR (0.83) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL22554404 | 0.83 | TSHR (0.83) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL22023212 | 0.83 | TSHR (0.83) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL22554406 | 0.83 | TSHR (0.83) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL5607699 | 0.83 | TSHR (0.83) | TSHRPOLBAPEX1HTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170267703-A1 | METHOD FOR PREPARING A POLYORGANOSILOXANE AND A POLYORGANOSILOXANE | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2017-09-21 | — | — | US | disclosed |
| US-9751901-B2 | Method for preparing a polyorganosiloxane and a polyorganosiloxane | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2017-09-05 | — | — | US | disclosed |
| US-20170088566-A1 | METHOD FOR PREPARING A POLYORGANOSILOXANE AND A POLYORGANOSILOXANE | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2017-03-30 | — | — | US | disclosed |
| US-20160159827-A1 | METHOD FOR PREPARING A POLYORGANOSILOXANE AND A POLYORGANOSILOXANE | SHINETSU CHEMICAL CO (JP) | 2016-06-09 | — | — | US | disclosed |
| US-9340649-B2 | Method for preparing a polyorganosiloxane and a polyorganosiloxane | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2016-05-17 | — | — | US | disclosed |
| US-20150299397-A1 | METHOD FOR PREPARING A POLYORGANOSILOXANE AND A POLYORGANOSILOXANE | SHINETSU CHEMICAL CO (JP) | 2015-10-22 | — | — | US | disclosed |
| US-20140213809-A1 | METHOD FOR PREPARING A POLYORGANOSILOXANE AND A POLYORGANOSILOXANE | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2014-07-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160159827-A1 | METHOD FOR PREPARING A POLYORGANOSILOXANE AND A POLYORGANOSILOXANE | SCO2, HAO2, RIOX2 | TSHR 1922/4885POLB 1015/4885APEX1 1816/4885 |
| US-20170088566-A1 | METHOD FOR PREPARING A POLYORGANOSILOXANE AND A POLYORGANOSILOXANE | SCO2, HAO2, RPS4X | TSHR 1832/4885POLB 977/4885APEX1 992/4885 |
| US-20170267703-A1 | METHOD FOR PREPARING A POLYORGANOSILOXANE AND A POLYORGANOSILOXANE | SCO2, HAO2, RIOX2 | TSHR 1922/4885POLB 1015/4885APEX1 1816/4885 |
| US-20140213809-A1 | METHOD FOR PREPARING A POLYORGANOSILOXANE AND A POLYORGANOSILOXANE | SCO2, IPO4, HAO2 | TSHR 3714/4885POLB 317/4885APEX1 1080/4885 |
| US-20150299397-A1 | METHOD FOR PREPARING A POLYORGANOSILOXANE AND A POLYORGANOSILOXANE | SCO2, HAO2, RIOX2 | TSHR 1922/4885POLB 1015/4885APEX1 1816/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.