SCHEMBL15904247

SCHEMBL15904247

OC1c2ccccc2-c2cccc(-c3ccc(-c4ccc(-c5cccc6c5C(O)c5ccccc5-6)cc4)cc3)c21

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.39
MEN1 O00255 1/20 0.39
ALDH1A1 P00352 1/20 0.39
TP53 P04637 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2D6 P10635 1/20 0.39
MAPT P10636 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
KMT2A Q03164 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
HSD17B10 Q99714 1/20 0.39
CHRNB2 P17787 1/20 0.38
CHRNA4 P43681 1/20 0.38
HTR2B P41595 6/20 0.36
HTR7 P34969 5/20 0.35
EDNRB P24530 1/20 0.34
EDNRA P25101 1/20 0.34
HDAC3 O15379 1/20 0.33
HDAC4 P56524 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7324096 0.92 CHRNB2 (0.45) KDM4EMEN1ALDH1A1TP53CYP3A4
SCHEMBL22182269 0.89 KDM4E (0.35) KDM4EMEN1ALDH1A1TP53CYP3A4
Formic Acid SCHEMBL27894294 0.84 CHRNB2 (0.40) KDM4EMEN1ALDH1A1TP53CYP3A4
SCHEMBL27567815 0.81 CHRNB2 (0.42) KDM4EMEN1ALDH1A1TP53CYP3A4
Biphenyl SCHEMBL28941488 0.81 CHRNB2 (0.42) KDM4EMEN1ALDH1A1TP53CYP3A4
SCHEMBL7183892 0.78 ALDH1A1 (0.39) KDM4EMEN1ALDH1A1TP53CYP3A4
SCHEMBL27935289 0.78 ALDH1A1 (0.50) KDM4EMEN1ALDH1A1TP53CYP3A4
Biphenyl SCHEMBL27675541 0.78 CHRNB2 (0.44) KDM4EMEN1ALDH1A1TP53CYP3A4
SCHEMBL1261847 0.78 MEN1 (0.45) KDM4EMEN1ALDH1A1TP53CYP3A4
SCHEMBL11783880 0.78 HTR2B (0.51) KDM4EMEN1ALDH1A1TP53CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2948423-A1 ANTI-EXTRUSION COMPOSITIONS FOR SEALING AND WEAR COMPONENTS Delsper LP (US) 2015-12-02 EP claimed
WO-2014117110-A1 ANTI-EXTRUSION COMPOSITIONS FOR SEALING AND WEAR COMPONENTS GREENE, TWEED TECHNOLOGIES, INC. (US) 2014-07-31 WO claimed
EP-2948423-A1 ANTI-EXTRUSION COMPOSITIONS FOR SEALING AND WEAR COMPONENTS Delsper LP (US) 2015-12-02 EP disclosed
WO-2014117110-A1 ANTI-EXTRUSION COMPOSITIONS FOR SEALING AND WEAR COMPONENTS GREENE, TWEED TECHNOLOGIES, INC. (US) 2014-07-31 WO disclosed