Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20123183 | 0.90 | ALDH1A1 (0.39) | ALDH1A1MAPK1KDM4EMEN1TP53 | |
| SCHEMBL15904247 | 0.78 | KDM4E (0.39) | ALDH1A1KDM4EMEN1TP53CYP3A4 | |
| SCHEMBL7324096 | 0.78 | CHRNB2 (0.45) | ALDH1A1MAPK1KDM4EMEN1TP53 | |
| SCHEMBL28456656 | 0.78 | HTR2B (0.40) | ALDH1A1MAPK1KDM4EMEN1TP53 | |
| SCHEMBL27935289 | 0.77 | ALDH1A1 (0.50) | ALDH1A1KDM4EMEN1TP53CYP3A4 | |
| SCHEMBL9122691 | 0.77 | KDM1A (0.40) | ALDH1A1MAPK1MEN1KMT2AHSD17B10 | |
| SCHEMBL11783880 | 0.76 | HTR2B (0.51) | ALDH1A1KDM4EMEN1TP53CYP3A4 | |
| SCHEMBL1261847 | 0.76 | MEN1 (0.45) | ALDH1A1KDM4EMEN1TP53CYP3A4 | |
| SCHEMBL18456445 | 0.74 | KDM4E (0.39) | ALDH1A1KDM4EMEN1TP53CYP3A4 | |
| SCHEMBL28865931 | 0.74 | PPIA (0.46) | ALDH1A1KDM4EMEN1TP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1059299-B1 | Process for the polymerisation of olefins in the presence of indenyl compounds | SABIC POLYPROPYLENES BV (NL) | 2003-12-17 | — | — | EP | disclosed |
| US-6342622-B1 | COMPOUNDS HAVING BRIDGING GROUP CONTAINING AT LEAST ONE SP2-HYBRIDISED CARBON ATOM BONDED TO INDENYL GROUP AT 2-POSITION ARE MORE ACTIVE AND/OR GIVE POLYMERS WITH HIGHER MOLECULAR WEIGHT | DSM B.V. (NL) | 2002-01-29 | — | — | US | disclosed |
| EP-1059299-A1 | Indenyl compounds for the polymerisation of olefins | DSM N.V. (NL) | 2000-12-13 | — | — | EP | disclosed |
| EP-1059300-A1 | Indenyl compounds for the polymerisation of olefins | DSM N.V. (NL) | 2000-12-13 | — | — | EP | disclosed |