Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | CA2 | P00918 | 8/20 | 0.58 |
| ▸ | CA1 | P00915 | 5/20 | 0.58 |
| ▸ | PPARG | P37231 | 2/20 | 0.54 |
| ▸ | PPARA | Q07869 | 1/20 | 0.54 |
| ▸ | DGAT1 | O75907 | 3/20 | 0.44 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15904110 | 0.89 | CA2 (0.59) | NPSR1CA2CA1PPARGPPARA | |
| SCHEMBL15904568 | 0.85 | CA2 (0.62) | NPSR1CA2CA1PPARGPPARA | |
| SCHEMBL15904203 | 0.84 | CA2 (0.56) | NPSR1CA2CA1DGAT1 | |
| SCHEMBL17313731 | 0.82 | MEN1 (0.40) | NPSR1CA2SLC1A2 | |
| SCHEMBL16283451 | 0.81 | CA2 (0.61) | NPSR1CA2CA1PPARGPPARA | |
| SCHEMBL4682406 | 0.80 | CA2 (0.65) | NPSR1CA2CA1PPARGPPARA | |
| SCHEMBL4682399 | 0.80 | CA2 (0.65) | NPSR1CA2CA1PPARGPPARA | |
| SCHEMBL17313750 | 0.80 | MEN1 (0.45) | — | |
| SCHEMBL9462009 | 0.80 | SLC1A2 (0.66) | NPSR1CA2CA1PPARGPPARA | |
| SCHEMBL1168553 | 0.80 | SLC1A2 (0.66) | NPSR1CA2CA1PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9663488-B2 | Metalloenzyme inhibitor compounds | VIAMET PHARMACEUTICALS, INC. (US) | 2017-05-30 | — | — | US | disclosed |
| US-20150353546-A1 | METALLOENZYME INHIBITOR COMPOUNDS | Viamet Pharmaceuticals (NC), Inc. | 2015-12-10 | — | — | US | disclosed |
| EP-2948450-A1 | METALLOENZYME INHIBITOR COMPOUNDS | Viamet Pharmaceuticals, Inc. (US) | 2015-12-02 | — | — | EP | disclosed |
| WO-2014117090-A1 | METALLOENZYME INHIBITOR COMPOUNDS | VIAMET PHARMACEUTICALS, INC. (US) | 2014-07-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150353546-A1 | METALLOENZYME INHIBITOR COMPOUNDS | MMEL1, GPX1, MPO | NPSR1 2998/4885CA2 209/4885CA1 356/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.