SCHEMBL159054

SCHEMBL159054

CC[CH]c1ccc(N(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.48
L3MBTL1 Q9Y468 3/20 0.48
MAPT P10636 2/20 0.48
KDM4E B2RXH2 2/20 0.48
CYP1A2 P05177 1/20 0.48
CYP3A4 P08684 1/20 0.48
CYP2D6 P10635 1/20 0.48
CYP2C9 P11712 1/20 0.48
CYP2C19 P33261 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
MEN1 O00255 6/20 0.44
KMT2A Q03164 6/20 0.44
SMN1; SMN2 Q16637 3/20 0.44
LMNA P02545 2/20 0.44
MAPK1 P28482 2/20 0.44
RELA Q04206 2/20 0.43
ALDH3A1 P30838 1/20 0.43
ALDH1A3 P47895 1/20 0.43
TLR9 Q9NR96 2/20 0.41
CRHBP P24387 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7175025 0.81 RELA (0.48) ALDH1A1L3MBTL1MAPTKDM4ECYP1A2
SCHEMBL7175033 0.81 RELA (0.48) ALDH1A1L3MBTL1MAPTKDM4ECYP1A2
SCHEMBL332156 0.81 ALDH1A1 (0.39) ALDH1A1L3MBTL1MAPTKDM4ECYP1A2
SCHEMBL3012 0.80
SCHEMBL851178 0.79 ALDH1A1 (0.59) ALDH1A1L3MBTL1MAPTKDM4ECYP1A2
SCHEMBL13649928 0.79 ALDH1A1 (0.59) ALDH1A1L3MBTL1MAPTKDM4ECYP1A2
SCHEMBL181026 0.79 ALDH1A1 (0.59) ALDH1A1L3MBTL1MAPTKDM4ECYP1A2
SCHEMBL2199745 0.79 ALDH1A1 (0.59) ALDH1A1L3MBTL1MAPTKDM4ECYP1A2
SCHEMBL28032989 0.79 ALDH1A1 (0.59) ALDH1A1L3MBTL1MAPTKDM4ECYP1A2
SCHEMBL806444 0.78 RELA (0.60) ALDH1A1L3MBTL1MAPTKDM4ECYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10752780-B2 Chromophores for photochromic compositions useful for three dimensional display applications NITTO DENKO CORPORATION (JP) 2020-08-25 US disclosed
US-20180291207-A1 CHROMOPHORES FOR PHOTOCHROMIC COMPOSITIONS USEFUL FOR THREE DIMENSIONAL DISPLAY APPLICATIONS NITTO DENKO CORPORATION (JP) 2018-10-11 US disclosed
US-10077362-B2 Chromophores for photochromic compositions useful for three dimensional display applications NITTO DENKO CORPORATION (JP) 2018-09-18 US disclosed
US-20170044373-A1 CHROMOPHORES FOR PHOTOCHROMIC COMPOSITIONS USEFUL FOR THREE DIMENSIONAL DISPLAY APPLICATIONS NITTO DENKO CORPORATION (JP) 2017-02-16 US disclosed
WO-2015164390-A1 CHROMOPHORES FOR PHOTOCHROMIC COMPOSITIONS USEFUL FOR THREE DIMENSIONAL DISPLAY APPLICATIONS NITTO DENKO CORPORATION (JP) 2015-10-29 WO disclosed
US-9080000-B2 Method of forming a non-random copolymer DOW CORNING CORPORATION (US) 2015-07-14 US disclosed
US-8927062-B2 Method of preparing a substrate with a composition including an organoborane initiator DOW CORNING CORPORATION (US) 2015-01-06 US disclosed
US-8679585-B2 Ambient lithographic method using organoborane amine complexes DOW CORNING CORPORATION (US) 2014-03-25 US disclosed
US-20130341573-A1 PHOTOREFRACTIVE COMPOSITION COMPRISING ELECTROLYTES IN A PHOTOREFRACTIVE LAYER AND METHOD OF MAKING THEREOF NITTO DENKO CORPORATION (JP) 2013-12-26 US disclosed
US-20130341574-A1 PHOTOREFRACTIVE COMPOSITION AND DEVICE COMPRISING THE COMPOSITION NITTO DENKO CORPORATION (JP) 2013-12-26 US disclosed
WO-2006112926-A2 PHOTOREFRACTIVE COMPOSITION NITTO DENKO CORPORATION (JP) 2006-10-26 WO disclosed
EP-1664236-A1 PHOTOREFRACTIVE COMPOSITION Nitto Denko Corporation (JP) 2006-06-07 EP disclosed
EP-1578884-A2 POLYMER, PRODUCING METHOD THEREOF, AND PHOTOREFRACTIVE COMPOSITION NITTO DENKO CORPORATION (JP) 2005-09-28 EP disclosed
US-20050116209-A1 Image correction device ARIZONA BOARD OF REGENTS 2005-06-02 US disclosed
WO-2005023962-A1 PHOTOREFRACTIVE COMPOSITION NITTO DENKO CORPORATION (JP) 2005-03-17 WO disclosed
US-20050051758-A1 Polysiloxane with pendant triphenylamine groups; photoconductive (charge transport) and non-linear optical ability; sensitizers, plasticizers NITTO DENKO CORPORATION (JP) 2005-03-10 US disclosed
US-6809156-B2 ACRYLATE BASED POLYMERS HAVING CHARGE TRANSPORT AND NONLINEAR OPTICAL COMPONENTS; INJECTION OR EXTRUSION MOLDING WORKABILITY NITTO DENKO CORPORATION (JP) 2004-10-26 US disclosed
US-20040077794-A1 Fullerene-containing polymer, producing method thereof, and photorefractive composition NITTO DENKO CORPORATION (JP) 2004-04-22 US disclosed
US-6653421-B1 Addition copolymer with pendant carbazole and/or triphenylamine groups; photoconductive (charge transport) and non-linear optical ability; sensitizers, plasticizers NITTO DENKO CORPORATION (JP) 2003-11-25 US disclosed
WO-2003085065-A2 POLYMER, PRODUCING METHOD THEREOF, AND PHOTOREFRACTIVE COMPOSITION NITTO DENKO CORPORATION (JP) 2003-10-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180291207-A1 CHROMOPHORES FOR PHOTOCHROMIC COMPOSITIONS USEFUL FOR THREE DIMENSIONAL DISPLAY APPLICATIONS CRY1, RB1, BRD3 ALDH1A1 1681/4885L3MBTL1 1594/4885MAPT 478/4885
US-10752780-B2 Chromophores for photochromic compositions useful for three dimensional display applications CRY1, RB1, BRD3 ALDH1A1 1681/4885L3MBTL1 1594/4885MAPT 478/4885
US-10077362-B2 Chromophores for photochromic compositions useful for three dimensional display applications CRY1, RB1, BRD3 ALDH1A1 1681/4885L3MBTL1 1594/4885MAPT 478/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.