Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 6/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 3/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.48 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14010061 | 0.92 | BRD4 (0.54) | BRD4MEN1KMT2AMAPK1ALDH1A1 | |
| SCHEMBL12574001 | 0.89 | BRD4 (0.59) | BRD4MEN1KMT2AMAPK1ALDH1A1 | |
| SCHEMBL13899508 | 0.89 | MEN1 (0.59) | BRD4MEN1KMT2AMAPK1ALDH1A1 | |
| SCHEMBL14729121 | 0.88 | MEN1 (0.59) | BRD4MEN1KMT2AMAPK1ALDH1A1 | |
| SCHEMBL14010049 | 0.88 | BRD4 (0.56) | BRD4MEN1KMT2AMAPK1ALDH1A1 | |
| SCHEMBL14010059 | 0.87 | BRD4 (0.60) | BRD4MEN1KMT2AMAPK1ALDH1A1 | |
| SCHEMBL11892525 | 0.87 | BRD4 (0.50) | BRD4MEN1KMT2AMAPK1ALDH1A1 | |
| SCHEMBL14729123 | 0.87 | MEN1 (0.57) | BRD4MEN1KMT2AMAPK1ALDH1A1 | |
| SCHEMBL14010063 | 0.85 | BRD4 (0.48) | BRD4MEN1KMT2AMAPK1ALDH1A1 | |
| SCHEMBL2601911 | 0.85 | CA9 (0.59) | MEN1KMT2AMAPK1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8791227-B1 | Crosslinked aromatic polyimides and methods of making the same | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 2014-07-29 | — | — | US | disclosed |