SCHEMBL1590567

SCHEMBL1590567

O=C(O)Oc1ccc(Cl)c(Cl)c1O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 1/20 0.41
FABP3 P05413 1/20 0.39
CYP3A4 P08684 1/20 0.37
MAPK1 P28482 1/20 0.37
AKR1B1 P15121 1/20 0.36
MRGPRX4 Q96LA9 1/20 0.36
TSHR P16473 4/20 0.35
CXCR1 P25024 1/20 0.35
CXCR2 P25025 1/20 0.35
HSD17B10 Q99714 2/20 0.34
HPGD P15428 1/20 0.34
CASP1 P29466 1/20 0.34
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
CSNK2A2 P19784 1/20 0.34
CSNK2B P67870 1/20 0.34
CSNK2A1 P68400 1/20 0.34
TTR P02766 2/20 0.33
TDP1 Q9NUW8 1/20 0.33
CLCN2 P51788 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL121773 0.83 FABP3 (0.51) DPP4FABP3CYP3A4MAPK1MRGPRX4
SCHEMBL31105888 0.83 FABP3 (0.51) DPP4FABP3CYP3A4MAPK1MRGPRX4
SCHEMBL10854654 0.80 MAPT (0.50) FABP3MRGPRX4TSHRHSD17B10HPGD
SCHEMBL6230446 0.77 CYP2C19 (0.38) DPP4CYP3A4MAPK1TSHRHSD17B10
SCHEMBL6233685 0.74 PPARG (0.37) TSHRNPC1RAB9A
SCHEMBL100191 0.73 TSHR (0.50) FABP3CYP3A4AKR1B1MRGPRX4TSHR
SCHEMBL9335491 0.72 MAPK1 (0.46) CYP3A4MAPK1AKR1B1TSHRHSD17B10
SCHEMBL9654332 0.72 HTT (0.37) DPP4CYP3A4MAPK1CSNK2A2CSNK2B
SCHEMBL7048087 0.72 KDM4E (0.33) DPP4MRGPRX4HSD17B10HPGDCASP1
SCHEMBL6232728 0.72 AKR1C2 (0.39) MAPK1TSHRHSD17B10HPGDNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8461072-B2 Late transition metal catalysts for olefin oligomerizations EXXONMOBIL CHEMICAL PATENTS INC. (US) 2013-06-11 US disclosed
US-7994086-B2 Late transition metal catalysts for olefin oligomerizations EXXONMOBIL CHEMICAL PATENTS INC. (US) 2011-08-09 US disclosed
US-20110092658-A1 Late Transition Metal Catalysts for Olefin Oligomerizations EXXONMOBIL CHEMICAL PATENTS INC. 2011-04-21 US disclosed
US-7247687-B2 Late transition metal catalysts for olefin polymerization and oligomerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-07-24 US disclosed
US-20060047094-A1 Late transition metal catalysts for olefin polymerization and oligomerization EXXONMOBIL CHEMICAL PATENTS INC. 2006-03-02 US disclosed
EP-1521758-A1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION Exxonmobil Chemical Patents Inc. (US) 2005-04-13 EP disclosed
WO-2004007509-A1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2004-01-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060047094-A1 Late transition metal catalysts for olefin polymerization and oligomerization MLX, LOX, LMTK3 DPP4 2340/4885FABP3 3996/4885CYP3A4 1449/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.