SCHEMBL100191

SCHEMBL100191

O=C(O)Oc1cccc(Cl)c1Cl

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.50
MRGPRX4 Q96LA9 1/20 0.47
HTR1D P28221 2/20 0.43
KMT2A Q03164 4/20 0.42
ALDH1A1 P00352 2/20 0.42
GAA P10253 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
HTT P42858 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
AKR1B1 P15121 1/20 0.41
ERCC5 P28715 1/20 0.41
FEN1 P39748 1/20 0.41
KDM4E B2RXH2 1/20 0.40
MEN1 O00255 2/20 0.40
TP53 P04637 1/20 0.40
CYP1A2 P05177 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2D6 P10635 1/20 0.40
CYP2C19 P33261 1/20 0.40
TDP1 Q9NUW8 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL180174 0.85 TSHR (0.47) TSHRMRGPRX4HTR1DKMT2AALDH1A1
SCHEMBL6969500 0.83 TSHR (0.45) TSHRMRGPRX4HTR1DKMT2AALDH1A1
SCHEMBL3918667 0.83 TSHR (0.45) TSHRMRGPRX4HTR1DKMT2AALDH1A1
SCHEMBL56864 0.83 PTK2B (0.50) TSHRKMT2AALDH1A1HTTMEN1
SCHEMBL9283420 0.82 KMT2A (0.45) TSHRMRGPRX4HTR1DKMT2AALDH1A1
SCHEMBL31612517 0.82 MAPK1 (0.49) TSHRMRGPRX4HTR1DKMT2AALDH1A1
SCHEMBL6691258 0.82 MAPK1 (0.49) TSHRMRGPRX4HTR1DKMT2AALDH1A1
SCHEMBL1639315 0.81 FABP4 (0.49) TSHRKMT2AALDH1A1MEN1TP53
SCHEMBL11330648 0.81 KMT2A (0.58) TSHRMRGPRX4KMT2AGAAHTT
Hydrochloric Acid SCHEMBL11843856 0.81 PTK2B (0.49) TSHRKMT2AALDH1A1HTTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 224 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1558664-B1 PREPARATION METHOD OF HIGH MOLECULAR WEIGHT POLYCARBONATE RESIN LG CHEMICAL LTD (KR) 2008-05-21 EP claimed
US-7148312-B2 Preparation method of high molecular weight polycarbonate resin LG CHEM, LTD. (KR) 2006-12-12 US claimed
US-20060167211-A1 Preparation method of high molecular weight polycarbonate resin LG CHEM, LTD. (KR) 2006-07-27 US claimed
EP-1558664-A1 PREPARATION METHOD OF HIGH MOLECULAR WEIGHT POLYCARBONATE RESIN LG Chem, Ltd. (KR) 2005-08-03 EP claimed
EP-1134248-B1 Process for the preparation of polycarbonate diols with a high molecular weight POLIMERI EUROPA SPA (IT) 2005-08-03 EP claimed
WO-2004041906-A1 PREPARATION METHOD OF HIGH MOLECULAR WEIGHT POLYCARBONATE RESIN LG CHEM, LTD. (KR) 2004-05-21 WO claimed
US-6384178-B2 COMPRISING TWO SUBSEQUENT REACTION STEPS, WHEREIN IN FIRST STEP POLYCARBONATE DIOL WITH MOLECULAR WEIGHT OF 500 TO 2000 IS SYNTHESIZED AND IN SECOND STEP MOLECULAR WEIGHT OF POLYCARBONATE DIOL IS INCREASED ENICHEM S.P.A. (IT) 2002-05-07 US claimed
US-20010047073-A1 Process for the preparation of polycarbonate diols with a high molecular weight ENICHEM S.P.A. (IT) 2001-11-29 US claimed
EP-1134248-A1 Process for the preparation of polycarbonate diols with a high molecular weight Enichem S.p.A. (IT) 2001-09-19 EP claimed
EP-4632024-A1 COATING MATERIAL AND METHOD FOR FORMING COATING LAYER NHK Spring Co., Ltd. (JP) 2025-10-15 EP disclosed
EP-4632023-A1 COATING MATERIAL, COATING LAYER, AND SPRING NHK Spring Co., Ltd. (JP) 2025-10-15 EP disclosed
EP-4632027-A1 COATING MATERIAL, COATING LAYER, AND SPRING NHK Spring Co., Ltd. (JP) 2025-10-15 EP disclosed
US-20250101173-A1 BIODEGRADABLE POLYCARBONATE COPOLYMER COMPRISING UNITS DERIVED FROM ANHYDROSUGAR ALCOHOL, ANHYDROSUGAR ALCOHOL-ALKYLENE GLYCOL, AND AROMATIC DIOL, METHOD FOR PRODUCING SAME, AND MOLDED PRODUCT COMPRISING SAME SAMYANG CORPORATION (KR) 2025-03-27 US disclosed
EP-4455187-A1 BIODEGRADABLE POLYCARBONATE COPOLYMER COMPRISING UNITS DERIVED FROM ANHYDROSUGAR ALCOHOL, ANHYDROSUGAR ALCOHOL-ALKYLENE GLYCOL, AND AROMATIC DIOL, METHOD FOR PRODUCING SAME, AND MOLDED PRODUCT COMPRISING SAME Samyang Corporation (KR) 2024-10-30 EP disclosed
US-4217437-A Process for the preparation of carbonic acid bis-diphenol esters of polyalkylene oxide-diols lengthened via carbonate groups and their use for the preparation of high-molecular, segmented polyether/polycarbonates which can be processed as thermoplastics BAYER AKTIENGESELLSCHAFT (DE) 1980-08-12 US disclosed
US-4217297-A Process for the preparation of carbonic acid aryl esters of polyester-diols lengthened via carbonate groups BAYER AKTIENGESELLSCHAFT (DE) 1980-08-12 US disclosed
US-4216298-A Process for the preparation of carbonic acid bis-diphenol esters of polyester-diols and their use for the preparation of high-molecular segmented polyester/polycarbonates which can be processed as thermoplastics BAYER AKTIENGESELLSCHAFT (DE) 1980-08-05 US disclosed
US-4191705-A Process for the preparation of carbonic acid esters of polyester-polyols BAYER AKTIENGESELLSCHAFT (DE) 1980-03-04 US disclosed
US-4066611-A CYCLIC DIPHOSPHITE GENERAL ELECTRIC COMPANY (US) 1978-01-03 US disclosed
US-4031165-A BLOCK COPOLYMER TEIJIN LIMITED (JA) 1977-06-21 US disclosed